Hot flashes, insomnia, and the reproductive stages: a cross-sectional observation of women from the EPISONO study

Hachul, Helena; Castro, Laura De; Bezerra, Andréia Gomes; Pires, Gabriel Natan; Poyares, Dalva; Andersen, Mônica Levy; Bittencourt, Lia Rita Azeredo; Tufik, Sérgio

doi:10.5664/jcsm.9432

Cited by 12 publications

(6 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other studies also demonstrate that postmenopausal women with decreased estrogen levels tend to have an increased sleep latency and reduced overall sleep time ( 39 ). Moreover, up to 80% of women experience severe hot flashes during menopause, and night sweats can lead to fragmented sleep and sleep interruptions, further curtailing sleep duration ( 42 ). These symptoms collectively highlight the intricate interplay between hormonal changes and sleep quality during the menopausal transition.…”

Section: Discussionmentioning

confidence: 99%

Association between sleep duration and depression in menopausal women: a population-based study

Zhang,

Cheng

2024

Front. Endocrinol.

View full text Add to dashboard Cite

AimsThis research investigated menopausal women older than 50 years to find whether there were any independent relationships between the duration of sleep they got and their prevalence of depression.MethodsNational Health and Nutrition Examination Survey (NHANES) datasets from 2011-2020 were utilized in a cross-sectional study. Using multivariate linear regression models, the linear relationship between sleep duration and depression in menopausal women was investigated. Fitted smoothing curves and thresholds impact evaluation were used to investigate the nonlinear relationship. Then, subgroup analyses were performed according to smoking, drinking alcohol, diabetes, hypertension, heart disease, and moderate activities.ResultsThis population-based study included a total of 3,897 menopausal women (mean age 65.47 ± 9.06 years) aged≥50 years; 3,159 had a depression score <10, and 738 had a depression score≥10. After controlling for all covariates, the prevalence of depression was 17% higher among participants with short sleep duration [OR=1.17, 95%CI=(0.65, 1.70), P<0.0001] and 86% [OR=1.86, 95%CI=(1.05, 2.66), P<0.0001] compared to participants with normal sleep duration. In subgroup analyses stratified by smoking and diabetes, the sleep duration and depression scores of non-smokers [β=-0.18, 95%CI= (-0.33, -0.02), P=0.0241] and diabetics were independently negatively correlated [β=-0.32, 95%CI= (-0.63, -0.01), P=0.0416]. Using a two-segment linear regression model, we discovered a U-shaped relationship between sleep duration and depression scores with an inflection point of 7.5 hours. Less than 7.5 hours of sleep was associated with an increased risk of developing depression [β=-0.81, 95%CI= (-1.05, -0.57), P<0.001]. However, sleeping more than 7.5 hours per night increased the risk of depression considerably [β=0.80, 95%CI= (0.51, 1.08), P<0.001].ConclusionsDepression is associated with sleep duration in menopausal women. Insufficient or excessive sleep may increase the risk of depression in menopausal women.

show abstract

Section: Discussionmentioning

confidence: 99%

Association between sleep duration and depression in menopausal women: a population-based study

Zhang,

Cheng

2024

Front. Endocrinol.

View full text Add to dashboard Cite

show abstract

“…En otro ámbito, Hachul y colaboradores realizaron un metaanálisis encontrando que las mujeres tienen mayores cambios en sus patrones del sueño respecto a los hombres esto es una consecuencia fisiológica de los cambios hormonales propios del ciclo menstrual, de consecuencia al llegar la menopausia con la desaparición de ciertas hormonas la mujer puede desarrollar insomnio el cual puede empeorar después de la posmenopausia (Hachul et al, 2021). Sin embargo, esto contradice lo encontrado en este estudio ya que el insomnio disminuyó considerablemente en posmenopausia Hybholt, afirma que, aparte de los molestos síntomas que sufre la mujer, en la cultura occidental la menopausia es percibida como la pérdida del atractivo sexual de la mujer, esto repercute en la salud emocional y mental de la mujer lo que deriva en síntomas depresivos (Hybholt, 2022).…”

Section: Discussionunclassified

Impacto del Climaterio en la Calidad de Vida de Mujeres un Centro de Atención Primaria de la Ciudad de Piñas

León Cordero,

Vivanco Pesantez,

Romero Encalada

2024

Ciencia Latina

View full text Add to dashboard Cite

Introducción: La calidad de vida es el grado de necesidades satisfechas y bienestar que el individuo refleja tanto a nivel psicológico, social, físico y espiritual, haciéndolo de manera independiente, no obstante, durante la menopausia la mujer experimenta una serie de cambios que pueden desencadenar enfermedades crónicas como osteoporosis o enfermedad cardiovascular. Objetivo: determinar la influencia de los signos y síntomas del climaterio en la calidad de vida de las mujeres. Materiales y métodos: se utilizó el método descriptivo-transversal, usando un muestreo por conveniencia, de mujeres en un rango etario de 45 a 55 años, para un total de 110 participantes voluntarias, el síntoma más frecuente durante las 3 etapas de la menopausia fue el dolor de cabeza con 16,5%; 15,5% y 15,1% respectivamente, contrastando al caso de la depresión/tristeza que inicialmente se refleja con un 14,7% y va disminuyendo en la perimenopausia 13,0% y desciende abruptamente a un 6,8%; en el caso de los dolores osteomusculares fluctúa entre 12,3%; 9,7% y 11,1%, de los síntomas que afectan el deseo sexual tenemos el 10,5%; 12,1% y 13,4%, el síntoma menos frecuente es nerviosismo/ansiedad 6,3%; 7,6% y 5,7%, Conclusión: la calidad de vida se ve afectada principalmente en las mujeres al inicio de la menopausia esto debido a la falta de educación sanitaria que tienen sobre esta etapa.

show abstract

“…The most prevalent conditions during this stage are anxiety, depression, and insomnia. [44][45][46][47][48] Anxiety and depression often coexist, manifesting as low mood, irritability, nervousness, and, in severe cases, even suicidal tendencies. A large cross-sectional study among Chinese women aged 40-60 years reported that 19.5% and 14.2% of perimenopausal and postmenopausal women, respectively, experienced symptoms of depression and anxiety.…”

Section: Menopause and Emotional Disordersmentioning

confidence: 99%

“…Research indicates that, compared with men, women experience more adverse life events, self-esteem issues, and reduced quality of life during menopause, significantly impacting the psychological well-being of perimenopausal and postmenopausal women. The most prevalent conditions during this stage are anxiety, depression, and insomnia 44-48 . Anxiety and depression often coexist, manifesting as low mood, irritability, nervousness, and, in severe cases, even suicidal tendencies.…”

Section: Menopause and Emotional Disordersmentioning

confidence: 99%

Effects of mind-body exercise on perimenopausal and postmenopausal women: a systematic review and meta-analysis

Xu,

Liu,

et al. 2024

Menopause

View full text Add to dashboard Cite

Importance The increasing attention to the management of perimenopausal and postmenopausal women parallels the growth of the aging population. Although hormone therapy is commonly used to alleviate menopausal symptoms, it carries a potential risk of cancer. Recently, mind-body exercises have emerged as innovative approaches for improving menopausal symptoms and bone health. However, research findings have needed to be more consistent, highlighting the significance of this study's systematic review of mind-body exercise effects on perimenopausal and postmenopausal women. Objective This study aims to evaluate the impact of mind-body exercises, including tai chi, yoga, Pilates, qigong, baduanjin, and mindfulness-based stress reduction, on bone mineral density, sleep quality, anxiety, depression, and fatigue among perimenopausal and postmenopausal women. Evidence Review Four electronic databases—PubMed, Embase, Cochrane Central Register of Controlled Trials, and Web of Science—were systematically searched from inception until July 2023. The search focused exclusively on randomized controlled trials to examine the impact of mind-body exercise interventions on perimenopausal and postmenopausal women. The methodological quality of the included studies was evaluated using the Cochrane Bias Risk Assessment tool. Findings A total of 11 randomized controlled trials, comprising 1,005 participants, were included in the analysis. Traditional meta-analysis indicated that mind-body exercise significantly enhanced bone mineral density in perimenopausal and postmenopausal women compared with control groups, with a standardized mean difference (SMD) of 0.41 (95% CI, 0.17 to 0.66; P = 0.001, I 2 = 7%). In addition, significant improvements were observed in sleep quality (SMD, −0.48; 95% CI, −0.78 to −0.17; P = 0.002, I 2 = 76%), anxiety reduction (SMD, −0.80; 95% CI, −1.23 to −0.38; P = 0.0002, I 2 = 84%), depressive mood (SMD, −0.80; 95% CI, −1.17 to −0.44; P < 0.0001, I 2 = 79%), and fatigue (SMD, −0.67; 95% CI, −0.97 to −0.37; P < 0.0001, I 2 = 0%). Conclusions and Relevance The findings of this meta-analysis demonstrate that mind-body exercise positively influences bone mineral density, sleep quality, anxiety, depression, and fatigue among perimenopausal and postmenopausal women.

show abstract

Hot flashes, insomnia, and the reproductive stages: a cross-sectional observation of women from the EPISONO study

Cited by 12 publications

References 47 publications

Association between sleep duration and depression in menopausal women: a population-based study

Association between sleep duration and depression in menopausal women: a population-based study

Impacto del Climaterio en la Calidad de Vida de Mujeres un Centro de Atención Primaria de la Ciudad de Piñas

Effects of mind-body exercise on perimenopausal and postmenopausal women: a systematic review and meta-analysis

Contact Info

Product

Resources

About