Hot Flashes and Related Outcomes in Breast Cancer Survivors and Matched Comparison Women

Carpenter, Janet S.; Johnson, David H.; Wagner, L; Andrykowski, Michael A.

doi:10.1188/02.onf.e16-e25

Cited by 176 publications

(154 citation statements)

References 32 publications

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“…Having sexual problems (or dysfunction) includes experiencing disturbances in sexual desire and physiological changes associated with loss of sexual desire and arousal, reduction in sexual pleasure, difficulty in achieving orgasm, anxiety about sexual performance, pain during intercourse, and not finding sex pleasurable (Laumann et al, 1994(Laumann et al, , 1999American Psychiatric Association, 1994;Greendale et al, 1996). Women treated for breast cancer by mastectomy and/or chemotherapy have also reported problems with sexual functioning (Ganz et al, 2004;Carpenter et al, 2002;Young-McCaughan, 1996;Ganz et al, 1998a) that is, those associated with treatmentrelated menopause (Ganz et al, 2003). Sexual problems and sexual functioning have been found to persist years after diagnosis with breast cancer (Ganz et al, 2002).…”

Section: Body Image Sexuality and Sexual Problemsmentioning

confidence: 99%

Body image and sexual problems in young women with breast cancer

et al. 2005

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SUMMARYPurpose: The purpose of this study was to determine the frequency of body image and sexual problems in the first months after treatment among women diagnosed with breast cancer at age 50 or younger.Background: Breast cancer treatment may have severe effects on the bodies of younger women. Surgical treatment may be disfiguring, chemotherapy may cause abrupt menopause, and hormone replacement is not recommended.Methods: A multi-ethnic population-based sample of 549 women aged 22-50 who were married or in a stable unmarried relationship were interviewed within seven months of diagnosis with in situ, local, or regional breast cancer.Results: Body image and sexual problems were experienced by a substantial proportion of women in the early months after diagnosis. Half of the 546 women experienced two or more body image problems some of the time (33%), or at least one problem much of the time (17%). Among sexually active women, greater body image problems were associated with mastectomy and possible reconstruction, hair loss from chemotherapy, concern with weight gain or loss, poorer mental health, lower self-esteem, and partner's difficulty understanding one's feelings. Among the 360 sexually active women, half (52%) reported having a little problem in two or more areas of sexual functioning (24%), or a definite or serious problem in at least one area (28%). Greater sexual problems were associated with vaginal dryness, poorer mental health, being married, partner's difficulty understanding one's feelings, and more body image problems, and there were significant ethnic differences in reported severity.Conclusions: Difficulties related to sexuality and sexual functioning were common and occurred soon after surgical and adjuvant treatment. Addressing these problems is essential to improve the quality of life of young women with breast cancer.

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Section: Body Image Sexuality and Sexual Problemsmentioning

confidence: 99%

Body image and sexual problems in young women with breast cancer

et al. 2005

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“…22,31 Breast cancer survivors report having hot flashes that are more frequent, severe, distressing, and stable over time in their frequency, severity, and distress compared with the general population. 32 Also, the presence of lymphedema and numbness that interferes with everyday functioning among long-term breast cancer survivors has been associated with greater PTSD symptoms, suggesting a long-term psychological impact of treatment-related medical sequelae. 13 Cognitive problems and neuropsychological sequelae.…”

Section: Group 1: Patients With Physical Sequelaementioning

confidence: 99%

Pathways for psychosocial care of cancer survivors

Holland

Reznik

2005

Cancer

133

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“…Approximately 65% of survivors experience hot flashes, with 59% rating the symptom as severe and 44% rating the symptom as extremely bothersome. In breast cancer survivors, unrelieved hot flashes are related to negative affect, fatigue, sleep difficulties, and overall poor quality of life [6].…”

Section: Introductionmentioning

confidence: 99%

Randomized, Double-Blind, Placebo-Controlled Crossover Trials of Venlafaxine for Hot Flashes After Breast Cancer

et al. 2007

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LEARNING OBJECTIVESAfter completing this course, the reader will be able to:1. Discuss the efficacy of venlafaxine in alleviating hot flashes and improving secondary outcomes.2. Identify the week of treatment that venlafaxine was most effective.3. List three side effects associated with venlafaxine.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit ™ at CME.TheOncologist.com CME CME ABSTRACT Background. Although venlafaxine reduces self-reported hot flashes, no data have established the drug's impact on physiologically documented hot flashes. Two randomized, double-blind, placebo-controlled crossover trials examined the efficacy of two doses of venlafaxine in relation to physiological and self-reported hot flashes and other outcomes, including negative affect, fatigue, sleep, and quality of life.Methods. Sample: 57 breast cancer survivors in the low-dose study; 20 in the high-dose study. Setting: university cancer clinics in the Southeast and Midwest. Intervention: 37.5 mg of venlafaxine (low-dose study) or 75 mg of venlafaxine (high-dose study). Measures: hot flash frequency (physiological monitor, diary, and event marker), hot flash severity (diary), hot flash bother (diary), and questionnaires for hot flash impact on daily life, negative affect, fatigue, sleep, and quality of life.

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Hot Flashes and Related Outcomes in Breast Cancer Survivors and Matched Comparison Women

Abstract: The findings guide the assessment of the uniqueness of the problem of hot flashes experienced by breast cancer survivors and help define outcomes to address in clinical practice or include in future hot flash intervention research.

Cited by 176 publications

References 32 publications

Body image and sexual problems in young women with breast cancer

Body image and sexual problems in young women with breast cancer

Pathways for psychosocial care of cancer survivors

Randomized, Double-Blind, Placebo-Controlled Crossover Trials of Venlafaxine for Hot Flashes After Breast Cancer

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