Hosta longipes inhibits melanogenesis by reducing expression of the melanocortin 1 receptor

Lee, Jin Woo; Kim, Young-Seok; Choi, Seon-Jun; Kim, Sung Hyeok; Ha, Chang Woo; Jang, Sohee; Chae, Doobyeong; Sung, Sikwon; Ham, Jungyeob; Sohn, Eun‐Hwa; Kim, Su‐Nam

doi:10.1007/s13273-021-00159-0

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…It was revealed that demethyleugenol β-D-glucopyranoside [ 85 ] and epicatechin-3-gallate [ 100 ] modulate the expression of MITF, TYR, TYRP-1 or TYRP-2. In addition, linolenic acid and linoleic acid significantly inhibit melanin production by blocking MRC1 signaling [ 77 ]. Arctigenin reduce the cellular cAMP level followed by supression of melanin production [ 86 ].…”

Section: In Vitro Studiesmentioning

confidence: 99%

Plants as Modulators of Melanogenesis: Role of Extracts, Pure Compounds and Patented Compositions in Therapy of Pigmentation Disorders

Merecz-Sadowska

Sitarek

Stelmach

et al. 2022

IJMS

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The kingdom of plants as a “green biofabric” of valuable bioactive molecules has long been used in many ailments. Currently, extracts and pure compounds of plant origin are used to aid in pigmentation skin problems by influencing the process of melanogenesis. Melanin is a very important pigment that protects human skin against ultraviolet radiation and oxidative stress. It is produced by a complex process called melanogenesis. However, disturbances in the melanogenesis mechanism may increase or decrease the level of melanin and generate essential skin problems, such as hyperpigmentation and hypopigmentation. Accordingly, inhibitors or activators of pigment formation are desirable for medical and cosmetic industry. Such properties may be exhibited by molecules of plant origin. Therefore, that literature review presents reports on plant extracts, pure compounds and compositions that may modulate melanin production in living organisms. The potential of plants in the therapy of pigmentation disorders has been highlighted.

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Section: In Vitro Studiesmentioning

confidence: 99%

Plants as Modulators of Melanogenesis: Role of Extracts, Pure Compounds and Patented Compositions in Therapy of Pigmentation Disorders

Merecz-Sadowska

Sitarek

Stelmach

et al. 2022

IJMS

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“…Since the embryos of zebrafish are transparent, it is easy to observe their morphology and the development of their organs (He et al, 2014;Park et al, 2020). Because of these advantages, zebrafish are an optimal animal model for toxicology studies that can also predict aquatic toxicity (An et al, 2021;Ha et al, 2021;Lee et al, 2021;.…”

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confidence: 99%

Mecoprop-p interrupts the development of zebrafish via apoptosis and vascular damage

Park

et al. 2022

J Anim Reprod Biotechnol

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To regulate the growth of broad leaf weeds in crop fields, chlorophenoxy herbicides, including dicamba, mecoprop, mecorpop-p, and 4-chloro-2-methylphenoxyacetic acid, are widely used (Sanchis et al., 2013;Mottier et al., 2014). The toxicities of several chlorophenoxy herbicides have been reported despite their widespread use. For example, 2,4-dichlorophenoxyacetic acid can cause cerebrovascular impairments in rats by damaging the structure of the plasma membrane (Elo et al., 1988;Bradberry et al., 2000). Mecoprop-p, another chlorophenoxy herbicide, is a synthetic auxin that has been widely used to control weed growth since the 1980s (Périllon et al., 2021). It is known to be poorly absorbed in the soil but has a high water solubility of 250 mg/L at 20℃

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Skin-whitening effects of Spergularia marina by suppressing MITF translocation

Kim

Sim

Nam

et al. 2023

Food Sci Biotechnol

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Hosta longipes inhibits melanogenesis by reducing expression of the melanocortin 1 receptor

Cited by 5 publications

References 28 publications

Plants as Modulators of Melanogenesis: Role of Extracts, Pure Compounds and Patented Compositions in Therapy of Pigmentation Disorders

Plants as Modulators of Melanogenesis: Role of Extracts, Pure Compounds and Patented Compositions in Therapy of Pigmentation Disorders

Mecoprop-p interrupts the development of zebrafish via apoptosis and vascular damage

Skin-whitening effects of Spergularia marina by suppressing MITF translocation

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