Host Innate Antiviral Response to Influenza A Virus Infection: From Viral Sensing to Antagonism and Escape
Wenlong An,
Simran Lakhina,
Jessica Leong
et al.
Abstract:Influenza virus possesses an RNA genome of single-stranded, negative-sensed, and segmented configuration. Influenza virus causes an acute respiratory disease, commonly known as the “flu” in humans. In some individuals, flu can lead to pneumonia and acute respiratory distress syndrome. Influenza A virus (IAV) is the most significant because it causes recurring seasonal epidemics, occasional pandemics, and zoonotic outbreaks in human populations, globally. The host innate immune response to IAV infection plays a… Show more
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