Host–Guest Mechanism via Induced Fit Fullerene Complexation in Porphin Receptor to Probe Salivary Alpha-Amylase in Dental Caries for Clinical Applications
Hira Asghar,
Sehrish Bilal,
Mian Hasnain Nawaz
et al.
Abstract:Salivary
α-amylase is the most abundant protein
of human
saliva that potentially binds to streptococcus and other bacteria
via specific surface-exposed α-amylase-binding proteins and
plays a significant role in caries development. The detection of α-amylase
in saliva can be used as a bioindicator of caries development. Herein,
a facile strategy has been applied, tailoring the photochemical properties
of 5,10,15,20-tetrakis(4-hydroxyphenyl)-21H,23H-porphine (TPPOH) and the fullerene C60 complex. The fluorescen… Show more
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