Host–guest complexation between cucurbit[7]uril and doxepin induced supramolecular assembly

Assaf, Khaleel I.

doi:10.1039/d2ob01065h

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2023

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“…A similar molecule, doxepin, has also been reported to form an inclusion complex with CB [7]. 39 It is noteworthy to mention here that the imipramine in our working solution is expected to be protonated since imipramine hydrochloride is used in the present work. Doubly protonated imipramine ion has not been observed in the mass spectrum.…”

Section: ■ Discussionmentioning

confidence: 89%

“…The 1 H NMR experiment in D 2 O suggests the presence of inclusion complexes in solution (see Figure S5). A similar molecule, doxepin, has also been reported to form an inclusion complex with CB[7] . It is noteworthy to mention here that the imipramine in our working solution is expected to be protonated since imipramine hydrochloride is used in the present work.…”

Section: Discussionmentioning

confidence: 94%

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