Host‐guest Assembly Based on γ‐Cyclodextrin‐functionalized Multiwalled Carbon Nanotubes for Rutin Electrochemical Sensing

Abstract

Here, we report multiwalled carbon nanotubes (MWCNTs) functionalized with γ‐cyclodextrins (γCD) as a novel electrochemical strategy for Rutin determination, showing superior performance than β‐cyclodextrins (βCD) modified MWCNTs, suggesting an adequate environment for host‐guest interactions. Under optimized conditions, the sensor showed a linear range of 39–975 nmol L−1 and a limit of detection of 7 nmol L−1. When tested with quercetin, catechin, and caffeine, the platform presented high selectivity with an interference response <10 %. The method was employed to quantify Rutin in spiked pharmaceutical and herbal extracts, providing recovery of 93–98.4 %. Also, HPLC‐PDA confirmed the method‘s accuracy.

First report on the electrooxidation of vinpocetine using a modification free sensing platform: application to pharmaceutical formulations

“…13,[19][20][21] From an analytical perspective, integrating electrochemical platforms with substrate modiers has been explored to enhance selectivity and/or sensitivity. [22][23][24][25][26][27] However, these approaches oen require multiple procedural steps, which may not consistently yield signicant results suitable for routine sample analyses. Plus, the characterization of the material is required, followed by its immobilization and electrochemical performance evaluation on the GCE surface.…”