Host-derived protease promotes aggregation of
Staphylococcus aureus
by cleaving the surface protein SasG
Heidi A. Crosby,
Klara Keim,
Jakub M. Kwiecinski
et al.
Abstract:Staphylococcus aureus
is one of the leading causes of hospital-acquired infections, many of which begin following attachment and accumulation on indwelling medical devices or diseased tissue. These infections are often linked to the establishment of biofilms, but another often overlooked key characteristic allowing
S. aureus
to establish persistent infection is the formation of planktonic aggregates. Such aggregates are physiologically similar to biofilms and protect p… Show more
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