Hospitalized children with 2009 influenza a (H1N1) infection in Shenzhen, China, november–december 2009

Zheng, Yuejie; He, Ying; Deng, Jikui; Lü, Zhiwei; Wei, Ju-Rong; Yang, Weiguo; Tang, Zhengzhen; Li, Boning; Zhang, Jaosheng; Wang, Li; Zhao, Hui; Li, Xiaonan; Yu, Zhenzhu; Song, Ping; Ma, Yijiao; Li, Yingfei; Li, Chengrong

doi:10.1002/ppul.21359

Cited by 16 publications

(20 citation statements)

References 22 publications

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“…We reviewed the data of 58 patients (28 males and 30 females; mean age 32 years) with myocarditis associated with H1N1pdm2009 worldwide [3, 31–62] and identified a high prevalence of fulminant myocarditis (36/58, 62%) among them. The characteristics of these 58 myocarditis patients are summarized in Table 1.…”

Section: Myocarditis Associated With Influenza H1n1pdm2009 In Thementioning

confidence: 99%

“…Bratincsák et al reported four patients with myocarditis associated with H1N1pdm2009 within a 30-day period in 2010 and suggested that H1N1pdm2009 virus might be more commonly associated with myocarditis than seasonal influenza virus [58]. Zheng et al reported finding seven children (5%) with complicated myocarditis among 148 children hospitalized with influenza H1N1pdm2009 infection in China [62]. Shin et al analyzed a group of 30 critically ill pediatric patients in Korea and reported that the most common causes of death were encephalopathy (four children) and myocarditis (four children) [63].…”

Section: Myocarditis Associated With Influenza H1n1pdm2009 In Thementioning

confidence: 99%

“…Our interest in influenza-associated myocarditis follows from our experience with the influenza pandemic of 2009 [3, 24–30]. We surveyed the literature for case reports and series involving myocarditis associated with H1N1pdm2009, and identified 58 patients with such a diagnosis [3, 31–62]. In the present study, we review the clinical, laboratory, and pathologic characteristics of these 58 patients and theorize about the pathogenesis of influenza myocarditis [63–68].…”

Section: Introductionmentioning

confidence: 99%

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Myocarditis Associated with Influenza A H1N1pdm2009

Ukimura

Satomi

Ooi

et al. 2012

Influenza Research and Treatment

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Acute myocarditis is a well-known complication of influenza infection. The frequency of myocardial involvement in influenza infection varies widely, with the clinical severity ranging from asymptomatic to fulminant varieties. The worst cases can result in death due to impaired cardiac function, although such fulminant myocarditis associated with influenza infection is rare, as shown by previous papers. Following the 2009 influenza pandemic, we reported on the clinical features of a cohort of 15 patients in Japan with H1N1pdm2009 myocarditis. In our subsequent survey of the literature for case reports or series of patients with myocarditis associated with H1N1pdm2009, we identified 58 detailed cases. We discuss here the high prevalence of fulminant myocarditis (36/58, 62%) among patients reported to have myocarditis associated with H1N1pdm2009. Mechanical circulatory support was required in 17 of the patients with fulminant myocarditis, 13 of whom recovered. We stress the need for increased awareness of influenza-associated myocarditis; such knowledge will facilitate earlier diagnosis and treatment of this fatal complication during future influenza pandemics.

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Section: Myocarditis Associated With Influenza H1n1pdm2009 In Thementioning

confidence: 99%

Section: Myocarditis Associated With Influenza H1n1pdm2009 In Thementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Myocarditis Associated with Influenza A H1N1pdm2009

Ukimura

Satomi

Ooi

et al. 2012

Influenza Research and Treatment

View full text Add to dashboard Cite

show abstract

“…Specifically, neurologic complications were more severe compared with seasonal influenza infection, and reached 30% of fl urelated deaths in England1). The incidence of neurologic complications in children was variously reported as 2% in Korea, 6% in England and the United States, and 12% in China1-4). Persistent neurologic symptoms were present in 22% of cases with H1N1 virus infection at the time of hospital discharge compared with, 0% of seasonal influenza cases3-6).…”

Section: Introductionmentioning

confidence: 99%

Secondary paroxysmal dyskinesia associated with 2009 H1N1 infection

Hur

Hwang

2013

Korean J Pediatr

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Neurological complications associated with 2009 H1N1 infection in children have been reported and recognized worldwide. The most commonly reported neurological complications are seizures and encephalopathy. Secondary movement disorders are also associated with the infection, but such cases are rarely reported. Here, we describe the case of a 14-year-old boy with paroxysmal kinesigenic dyskinesia secondary to 2009 H1N1 infection, who presented with dystonia and choreic movement triggered by sudden voluntary movement.

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“…In most cases, it presents with cough, coryza, sputum, fever, vomiting, and diarrhea. However, in rather rare cases, the H1N1 infection can also be rapidly progressive and may develop either an acute lung injury or an acute respiratory distress syndrome or even secondary bacterial infection, which may become an important cause of death in children and adolescent 1–12. Therefore, it is important to identify earlier which patients have higher risk of the severe pneumonia, e.g., immune‐suppressed persons, elderly, persons with underlying pulmonary or cardiac disease, pregnant women, persons with diabetes, children less than 5 years of age, and patients with bacterial co‐infection 1…”

Section: Introductionmentioning

confidence: 99%

Asymmetry in a pterobranch hemichordate and the evolution of left–right patterning

Sato

Holland

2008

Developmental Dynamics

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To investigate the possible origin of vertebrate asymmetry, we reexamined the long-described asymmetry of pterobranch hemichordates, a group of tiny, mostly colonial marine filter feeders. As first described over a century ago, we found left-right (LR) asymmetry in localization of the gonad. However, contrary to early descriptions, the direction of asymmetry is random, displaying antisymmetry rather than directional asymmetry. We found that the direction of gonad localization is significantly related to the shape of the tube in which the zooid lives. We also reexamined other anatomical features described to have directional asymmetry, the shape of the oral lamella and localization of the gonopore; however, we did not confirm asymmetry in these examples. Together with previous studies, our results suggest that hemichordates have undergone degeneration in the precision of asymmetry from an ancestral asymmetrical condition that existed before the divergence of deuterostomes. Developmental Dynamics 237:3634 -3639, 2008.

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Hospitalized children with 2009 influenza a (H1N1) infection in Shenzhen, China, november–december 2009

Abstract: Hospitalized children with 2009 influenza A (H1N1) infection can have a wide range of presentation and clinical complications including neurologic complications. The severe cases and deaths concentrate in previously healthy older children.

Cited by 16 publications

References 22 publications

Myocarditis Associated with Influenza A H1N1pdm2009

Myocarditis Associated with Influenza A H1N1pdm2009

Secondary paroxysmal dyskinesia associated with 2009 H1N1 infection

Asymmetry in a pterobranch hemichordate and the evolution of left–right patterning

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