Hospitalizations and Deaths Associated with EVALI

Werner, Angela; Koumans, Emilia H.; Chatham‐Stephens, Kevin; Salvatore, Phillip P.; Armatas, Christina; Byers, Paul D.; Clark, Charles R.; Ghinai, Isaac; Holzbauer, Stacy; Navarette, Kristen; Danielson, Melissa L.; Ellington, Sascha; Moritz, Erin D.; Petersen, Emily E.; Kiernan, Emily; Baldwin, Grant T.; Briss, Peter A.; Jones, Christopher M.; King, Brian A.; Krishnasamy, Vikram; Rose, Dale A.; Reagan‐Steiner, Sarah

doi:10.1056/nejmoa1915314

Cited by 149 publications

(124 citation statements)

References 31 publications

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“…Furthermore, the aerosols generated by these products typically contain a variety of substances including but not limited to nicotine, flavorings, additives and tetrahydrocannabinol (THC). 94 It is no surprise that recent studies have raised concerns about other potential serious side effects of the use of e-cigarettes. These include case reports of traumatic injury as a result of e-cigarette explosion as well as the emerging syndrome of e-cigarette, or vaping, product use-associated lung injury (EVALI).…”

Section: Challenges and Failures Of Smoking Cessationmentioning

confidence: 99%

“…These include case reports of traumatic injury as a result of e-cigarette explosion as well as the emerging syndrome of e-cigarette, or vaping, product use-associated lung injury (EVALI). [94][95][96] The emerging clinical syndrome of EVALI is of particular concern with the Center for Disease Control and Prevention reporting 60 cases that have ultimately resulted in the death of those affected. 94 It is important that clinicians are aware of these significant risks when counselling patients who are either currently using ecigarettes or considering its use a substitute for smoking cigarettes.…”

Section: Challenges and Failures Of Smoking Cessationmentioning

confidence: 99%

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The impact of tobacco smoking on treatment choice and efficacy in inflammatory bowel disease

et al. 2021

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horts. 3 It is well established that smoking significantly increases the risk of developing and worsens the disease course of CD, yet is protective against the development and reduces the severity of ulcerative colitis (UC). 4,5 However, what is less clear is whether smoking impacts the efficacy of therapeutics in IBD. Given the increased choice and availability of therapies with differing mechanisms of action, it may be surmised that for patients who continue smoking (i.e., failing efforts at cessation as is often encountered) there may be a preferred treatment option given a potential differential impact (positive, negative, or neutral) of smoking on individual treatments. Hence, the aim of this paper was to review the literature regarding the relationship between smoking and the efficacy of medical and surgical therapies in IBD, with particular reference to CD. A proposed algorithm for the approach to the management of IBD in smokers is proposed based on this review (Fig. 1).

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Section: Challenges and Failures Of Smoking Cessationmentioning

confidence: 99%

Section: Challenges and Failures Of Smoking Cessationmentioning

confidence: 99%

The impact of tobacco smoking on treatment choice and efficacy in inflammatory bowel disease

et al. 2021

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“…Although these devices may function as nicotine delivery systems to help adult cigarette smokers quit, they may also serve as a means to initiate or perpetuate nicotine addiction in adults and the youth. In addition, the potential dangers and health consequences of e-cigarette use were illustrated by the outbreak of e-cigarette, or vaping, associated lung injury (EVALI) [7,8]. Although many patients who developed EVALI used products containing tetrahydrocannabinol, some used devices containing only nicotine [9].…”

Section: Introductionmentioning

confidence: 99%

Improved Documentation of Electronic Cigarette Use in an Electronic Health Record

Jose

Hays

Warner

2020

IJERPH

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The use of electronic cigarettes (e-cigarettes) can affect patient health and clinical care. However, the current documentation of e-cigarette use in the electronic health records (EHR) is inconsistent. This report outlines how the ambulatory clinical practices of a large U.S. hospital system optimized its electronic health records (EHR) framework to better record e-cigarettes used by patients. The new EHR section for e-cigarette information was implemented for outpatient appointments. During a 30-week evaluation period post-implementation, 638,804 patients (12 yrs and older) completed ambulatory appointments within the health system; of these, the new section contained e-cigarette use information for 37,906 (6%) patients. Among these patients, 1005 (2.7%) were identified as current e-cigarette users (current every day or current some day e-cigarette use), 941 (2.5%) were reported as former e-cigarette users, and 35,960 (94%) had never used e-cigarettes. A separate EHR section to document e-cigarette use is feasible within existing clinical practice models. Utilization of the new section was modest in routine clinical practice, indicating the need for more intensive implementation strategies that emphasize the health effects of e-cigarette use, and how consistent ascertainment could improve clinical practice.

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“…Although never officially approved by the FDA, over the past few years, vaping/E-cigarettes has become a popular trend and has been considered "safer" alternative to smoking cigarettes, especially among young adults. The use of Ecigarettes has rapidly increased, and according to the most recent report by CDC released at the end of December 2019, 2506 cases of lung disease and more than 54associated deaths due to EVALI were reported [19]. Initial data shows that most patients use E cigarettes containing tetrahydrocannabinol (THC); some use nicotine while others used a combination of both nicotine and THC.…”

Section: Discussionmentioning

confidence: 99%

Deadly combination of Vaping-lnduced lung injury and Influenza: case report

Akkanti¹,

Hussain²,

Patel³

et al. 2020

Diagn Pathol

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Background: E-cigarette and vaping use-associated acute lung injury (EVALI) has been recently recognized as a complication in individuals who use vaping devices. Another consideration is that EVALI may have an adverse influence on the outcome of intercurrent respiratory infections. We document this deadly combination in the case of a young man who had EVALI and simultaneous Influenza-A infection leading to severe Acute Respiratory Distress Syndrome (ARDS). Case presentation: A 27-year-old male with a history of tobacco and vaping use was admitted to hospital after two weeks of flu-like symptoms, diarrhea and vomiting. A chest x-ray was consistent with multifocal pneumonia, and microbiological tests were positive for Influenza-A and methicillin-sensitive Staphalacoccus aureus (MSSA). Bronchoscopy provided evidence of acute inhalational injury. After admission, he acutely decompensated with severe hypoxia and hypotension; he required intubation, sedation and vasopressors. He developed sepsis with acute kidney failure, liver failure, biventricular systolic dysfunction and severe rhabdomyolysis. He was placed on veno-venous (VV) extracorporeal membrane oxygenation (ECMO) initially and later changed to Veno-Arterial (VA) ECMO. Nevertheless, the patient continued to deteriorate, and he expired two weeks after admission. Conclusion: This case documents that EVALI can act as a major factor leading a respiratory infection to progress into severe ARDS with a fatal outcome.

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Hospitalizations and Deaths Associated with EVALI

Cited by 149 publications

References 31 publications

The impact of tobacco smoking on treatment choice and efficacy in inflammatory bowel disease

The impact of tobacco smoking on treatment choice and efficacy in inflammatory bowel disease

Improved Documentation of Electronic Cigarette Use in an Electronic Health Record

Deadly combination of Vaping-lnduced lung injury and Influenza: case report

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