Hospital Morbidity Database for Epidemiological Studies on Churg-Strauss Syndrome

Kanecki, Krzysztof; Nitsch–Osuch, Aneta; Goryński, Paweł; Tarka, Patryk; Tyszko, Piotr

doi:10.1007/5584_2017_8

Cited by 12 publications

(9 citation statements)

References 22 publications

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“…Male to female ratio was 1:1 for GPA and MPA, and 1:2 in for EGPA. This corresponds to other recently published Polish report [21] and, unexpectedly, to data obtained in the Japanese population [22], but differs from the results published by French Vasculitis Study Group and from Spain [19,20]. As the proportion of anti-MPO positive and anti-MPO negative EGPA patients in our cohort was similar to the one observed in other European countries [2], higher proportion of women in our registry may represent a true difference between Central and South-Western Europe.…”

Section: Discussionsupporting

confidence: 93%

Clinical characteristics of Polish patients with ANCA-associated vasculitides—retrospective analysis of POLVAS registry

et al. 2019

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Objective Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare small to medium-size vessel systemic diseases. As their clinical picture, organ involvement, and factors influencing outcome may differ between countries and geographical areas, we decided to describe a large cohort of Polish AAV patients coming from several referral centers-members of the Scientific Consortium of the Polish Vasculitis Registry (POLVAS). Methods We conducted a systematic multicenter retrospective study of adult patients diagnosed with AAV between Jan 1990 and Dec 2016 to analyze their clinical picture, organ involvement, and factors influencing outcome. Patients were enrolled to the study by nine centers (14 clinical wards) from seven Voivodeships populated by 22.3 mln inhabitants (58.2% of the Polish population). Results Participating centers included 625 AAV patients into the registry. Their distribution was as follows: 417 patients (66.7%) with GPA, 106 (17.0%) with MPA, and 102 (16.3%) with EGPA. Male-to-female ratios were almost 1:1 for GPA (210/207) and MPA (54/52), but EGPA was twice more frequent among women (34/68). Clinical manifestations and organ involvement were analyzed by clinical phenotype. Their clinical manifestations seem very similar to other European countries, but interestingly, men with GPA appeared to follow a more severe course than the women. Fifty five patients died. In GPA, two variables were significantly associated with death: permanent renal replacement therapy (PRRT) and respiratory involvement (univariate analysis). In multivariate analysis, PRRT (OR = 5.3; 95% confidence Electronic supplementary material The online version of this article (

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Section: Discussionsupporting

confidence: 93%

Clinical characteristics of Polish patients with ANCA-associated vasculitides—retrospective analysis of POLVAS registry

et al. 2019

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“…Table 1 presents the results of conducted and published studies on the epidemiology of rare rheumatic diseases, including rare systemic vasculitides. The studies concerned diseases such as Behçet›s disease [25], Churg-Strauss Syndrome [26], Kawasaki disease [27], Polyarteritis nodosa [28], and Granulomatosis with polyangiitis [29]. The results obtained in these studies were positively verified against data from other sources of world scientific literature.…”

Section: Diagnosis Of the Underlying Disease And Commodities Accordinmentioning

confidence: 62%

Use of statistical data concerning hospital morbidity in epidemiological studies on rare rheumatic diseases

Kanecki¹,

Nitsch–Osuch²,

Goryński³

et al. 2018

Med Og Nauk Zdr.

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Introduction. Data validity constitutes a fundamental problem in epidemiology. An accurate estimate of the occurrence of a rare disease may require a large population study. In the case of rare diseases, all available data resources are used to estimate the occurrence rate, including statistical data concerning hospital morbidity. For life-threatening systemic vasculitides an analysis of its epidemiology is of particular importance. Objective. The main aim of the study was to present the possibilities for the use of data from hospital databases in an analysis of the epidemiology of rare diseases, using the example of particular systemic vasculitides. Results. The study shows the results of analyses performed on a population-based administrative data set concerning systemic vasculitides taken from the national hospital morbidity database prepared by the Polish National Institute of Public Health in 2004-2013. The study also discusses the main advantages and limitations of the adapted methodology. Furthermore, it proves that data from hospital databases can be used for analyzing disease incidence and prevalence, gender and territorial distribution, analysis of hospital mortality (fatality) rates, and trends in long-term observations. Conclusion. An analysis of the epidemiology of rare rheumatic diseases can contribute to a better understanding of their specificity, which can be useful in everyday clinical practice.

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“…The data of NGHMS were used for scientific purposes as soon as in the 1970s (4-6), whereas in the 1980s they were used, among others, in major studies comparing the various aspects of hospitalisation in Poland and in USA (7,8). The papers being written are directly relevant to hospital treatment (for instance, the frequency of the occurrence of in-hospital cardiac arrest (9), hospitalisation caused by obesity (10) or asthma (11)), but, as well, the seasonality of health phenomena (12), their spatial differences (13), the effectiveness of vaccinations (14,15), the prevalence of rare diseases (16)(17)(18)(19) -in that case, the NGHMS replaced non-existent registries of diseases. Data acquired from the Study are also annually published by the Statistics Poland in the reports entitled 'Health and health care in … ' (20).…”

Section: Analyses Based On the Results Of Nghmsmentioning

confidence: 99%

“…Hospitalisations due to ill-defined conditions (according to ICD-10 -Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified, R00-R99) are an issue combining the problem of medical care and the quality of data. In spite of the fact that both in Poland and elsewhere in the world it is recommended that such diagnoses be restricted as the main cause of hospitalisation (1, 2), in our country they constitute nearly 5% of the total number (in the case of children and adolescents, the percentage is significantly higher, namely, in the year 2017, such was a diagnosis in the case of 8.9% hospitalised at the age: 5-14, and 10.3% at the age: [14][15][16][17][18][19]. Most frequently (in more than 30%) such diagnoses are observed in the case of abdominal and pelvic pain (R10), followed by pain in the throat and Lepsza jakość danych o hospitalizacjach umożliwiłaby prowadzenie przez wszystkich zainteresowanych bardziej precyzyjnych analiz, w tym służących realizacji zobowiązań wobec organizacji międzynarodowych (WHO, OECD).…”

Section: Limitations Of the Studymentioning

confidence: 99%

“…Powstające artykuły dotyczą bezpośrednio leczenia szpitalnego (np. częstości występowania wewnątrzszpitalnego nagłego zatrzymania krążenia (9), hospitalizacji z powodu otyłości (10) czy astmy (11)), ale również sezonowości i przestrzennego zróżnicowania zjawisk zdrowotnych (12,13), skuteczności szczepień (14,15), rozpowszechnienia chorób rzadkich (16)(17)(18)(19) -w tym wypadku OBChSO zastępuje nieistniejące rejestry chorób. Dane z badania trafiają również do wydawanych corocznie przez GUS raportów pt.…”

Section: Wykorzystanie Wynikówunclassified

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Nationwide General Hospital Morbidity Study as a source of data about Polish population health

et al. 2019

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The objective of this article is description of the important source of data on hospitalised morbidity collected in Poland within the frameworks of public statistics, and also underlying the significance of the quality of data collected at the hospital level for the purpose of the practical application of them. The Nationwide General Hospital Morbidity Study has been conducted by the Department of Population Health Monitoring and Analysis of the NIPH-NIH for more than 40 years within the frameworks of the Programme of Statistical Surveys of Official Statistics. Since the year 2000, it has had a complete character, collecting individual data for all cases of hospitalisation in Poland within the scope compliant with the MZ/Szp-11 form, among others, sex, age, place of residence of a patient, data on hospital, information about the course of treatment (length of stay in hospital, principal diagnosis and comorbidity, applied medical procedures, the mode of admission and discharge). The collected data are anonymous. In the recent years, annually, more than 8 million of the cases of hospitalisation have been documented. Almost all obliged hospitals (96%) participate in the study. Some weak point is the completeness of submitted data, in particular, regarding information about the external causes of injuries and poisonings (in the year 2017, 27% of the required data were missing). Interestingly, a high level of missing data is generated by a comparatively small number of hospitals. Significant differences are observed in the quality of data depending on the voivodship of hospital location. The collected data render it possible to, among others, determine the frequency of hospitalisations due to particular causes taking under consideration the localisation of a hospital, and also the sex, age and the place of residence of patients, the analysis of the duration of hospital stay or in-hospital fatality. The aggregated results are reported to international databases (WHO, OECD, Eurostat), and support the administrative authorities of various levels. They are also a basis for numerous published scientific papers. The most important results of routine analyses are presented of the web page of the Study (http://www.statystyka1.medstat.waw.pl/).

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Hospital Morbidity Database for Epidemiological Studies on Churg-Strauss Syndrome

Cited by 12 publications

References 22 publications

Clinical characteristics of Polish patients with ANCA-associated vasculitides—retrospective analysis of POLVAS registry

Clinical characteristics of Polish patients with ANCA-associated vasculitides—retrospective analysis of POLVAS registry

Use of statistical data concerning hospital morbidity in epidemiological studies on rare rheumatic diseases

Nationwide General Hospital Morbidity Study as a source of data about Polish population health

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