Hospital burden of vertebral fractures in France: influence of vertebroplasty

Maravic, Milka; Taupin, Pierre; Roux, Christian

doi:10.1007/s00198-012-2264-7

Cited by 13 publications

(19 citation statements)

References 23 publications

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“… 497 ≥65 Plain lateral radiographs of thoracic and lumbar spine with collapse of the anterior and posterior borders at >15% of its normal height Levy et al [ 19 ] America Evaluate outcomes in vertebral fragility fracture patients treated operatively and non-operatively over 10 years. 250 Not stated ICD-9 (cod 805.2, 805.4) Maravic et al [ 20 ] France Study of hospital burden and outcomes of patients treated with vertebroplasty or non-operatively admitted into French hospitals with vertebral fragility fractures identified from the 2009 French Hospital National Database. Data collected from admission till 1 year after hospitalisation.…”

Section: Resultsmentioning

confidence: 99%

“…Seven studies reported the incidence of hospital admission with vertebral fragility fracture using large national hospital databases of Spain [ 8 ], America [ 9 ], Hungary [ 12 ], Italy [ 13 ], Sweden [ 17 ] and France [ 20 ]; and Medicare, an American national insurance programme dataset [ 10 ]. There was geographical variation in the overall incidence of hospital admission from 2.8 to 19.3 per 10,000/year (Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…In total, 10 studies [ 7 – 10 , 13 , 14 , 17 , 18 , 20 , 25 ] were considered fully representative of a hospitalised vertebral fragility fracture cohort using the NOS assessment of study quality. The pooled, weighted, proportion of women in these studies was 65% (range: 57–84%).…”

Section: Resultsmentioning

confidence: 99%

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Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review

et al. 2017

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Backgroundthe complex management for patients presenting to hospital with vertebral fragility fractures provides justification for the development of specific services for them. A systematic review was undertaken to determine the incidence of hospital admission, patient characteristics and health outcomes of vertebral fragility fracture patients to inform the development of such a service.Methodsnon-randomised studies of vertebral fragility fracture in hospital were included. Searches were conducted using electronic databases and citation searching of the included papers.Resultsa total of 19 studies were included. The incidence of hospital admission varied from 2.8 to 19.3 per 10,000/year. The average patient age was 81 years, the majority having presented with a fall. A diagnosis of osteoporosis or previous fragility fracture was reported in around one-third of patients. Most patients (75% men and 78% women) had five or more co-pathologies. Most patients were managed non-operatively with a median hospital length of stay of 10 days. One-third of patients were started on osteoporosis treatment. Inpatient and 1-year mortality was between 0.9 and 3.5%, and 20 and 27%, respectively, between 34 and 50% were discharged from hospital to a care facility. Many patients were more dependent with activities of daily living on discharge compared to their pre-admission level. Older age and increasing comorbidities was associated with longer hospital stay and higher mortality.Conclusionthese findings indicate that specific hospital services for patients with vertebral fragility fractures should take into consideration local hospitalisation rates for the condition, and should be multifaceted—providing access to diagnostic, therapeutic, surgical and rehabilitation interventions.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review

et al. 2017

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“…Of note, the attending physicians were masked as to the procedure, so that discharge decisions were based on clinical improvement rather than treatment allocation. Shorter inpatient hospital stays and lower readmission rates for patients treated with VA have been described previously 36 37…”

Section: Prospective Randomized Blinded Outcome Controlled Trialsmentioning

confidence: 76%

The evidentiary basis of vertebral augmentation: a 2019 update

Leacy

Chandra

Barr

et al. 2020

J NeuroIntervent Surg

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No aspect of neurointerventional practice has been associated with as longstanding contention and debate as to its effectiveness as has vertebroplasty (VP). Four blinded randomized controlled trials published since 2009 have demonstrated conflicting results regarding a conferred benefit in pain reduction and functional improvement for patients who undergo VP for osteoporotic vertebral compression fractures. Significant heterogeneity exists between each of these trials, which has resulted in difficulty for interventionalists and surgeons to translate the trial findings into routine clinical practice. In addition, patients and their families are ever more enlightened and enabled via the internet and social media to review both medical literature and websites. Without the proper background and context, their decisions may be lacking appropriate and necessary scientific discussion. This review article summarizes the randomized controlled trial data to date, with particular focus on the aforementioned four blinded studies. We will also evaluate the profound impact of the decrease in vertebral augmentation utilization on short- and long-term patient morbidity and mortality using available national and administrative datasets from both within the USA and internationally. We also consider future trial design to help evaluate this procedure and determine its role in modern neurointerventional practice.

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“…An analysis of 13,624 hospitalized patients with VCFs from the French Hospital National Database demonstrated that a higher proportion of patients are discharged in 7 days after vertebroplasty compared with medical management (68% versus 47%, P Ͻ .001). 60 A large Taiwanese study using National Health Insurance data for 9238 hospitalized patients with VCFs demonstrated a 2-day-earlier discharge and lower 30-day readmission rates after vertebroplasty.…”

Section: Hospital Admissionmentioning

confidence: 98%

Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?

Chandra

Maingard

Asadi

et al. 2017

AJNR Am J Neuroradiol

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SUMMARY:Osteoporotic vertebral compression fractures frequently result in significant morbidity and health care resource use. For patients with severe and disabling pain, vertebral augmentation (vertebroplasty and kyphoplasty) is often considered. Although vertebroplasty was introduced Ͼ30 years ago, there are conflicting opinions regarding the role of these procedures in the treatment of osteoporotic vertebral compression fractures. This review article updates clinicians on the published prospective randomized controlled data, including the most recent positive trials that followed initial negative trials in 2009. Analysis of multiple national claim datasets has also provided further insight into the utility of these procedures. Finally, we considered the recent recommendations of national organizations and medical societies that advise on the use of vertebral augmentation procedures for osteoporotic vertebral compression fractures. ABBREVIATIONS:NRS ϭ numeric rating scale; PMMA ϭ polymethylmethacrylate; QUALEFFO ϭ Quality of Life Questionnaire of the European Foundation for

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Hospital burden of vertebral fractures in France: influence of vertebroplasty

Abstract: This is the first French study assessing the national burden of vertebral fractures based on hospital data. In-hospital death rate is lower in patients with vertebroplasty, who are younger and have less comorbidities than the general population with vertebral fractures.

Cited by 13 publications

References 23 publications

Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review

Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review

The evidentiary basis of vertebral augmentation: a 2019 update

Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?

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