Hospital-based surveillance of rotavirus gastroenteritis in the era of limited vaccine uptake through the private sector

Trimis, Georgios; Koutsoumbari, Ioanna; Kottaridi, Christine; Palaiologou, Nikoletta; Assimakopoulou, Efstathia; Spathis, Aris; Lebessi, Evangelia; Konstantopoulos, Andreas; Kafetzis, Dimitris A.; Karakitsos, Petros; Papaevangelou, Vassiliki

doi:10.1016/j.vaccine.2011.07.092

Cited by 24 publications

(19 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This public health benefit could only be achieved because of the good performance of the rotavirus vaccination [15] in combination with a high coverage, although recent studies in Europe demonstrated that even a low rotavirus vaccine uptake may have significant effects on the disease burden [25,26].…”

Section: Resultsmentioning

confidence: 99%

Rotavirus vaccination coverage and adherence to recommended age among infants in Flanders (Belgium) in 2012

et al. 2014

View full text Add to dashboard Cite

In Belgium, rotavirus vaccination has been recommended and partially reimbursed since October 2006. Through a retrospective survey in 2012, we estimated the coverage rate of the rotavirus vaccination in Flanders among infants born in 2010. Using a standardised questionnaire, 874 families were interviewed at home, collecting information on demographic characteristics, socio-economic background and documented vaccination history (updated from medical files and vaccination database, if needed). Adherence to the recommended age for vaccination (8, 12 and 16 weeks) was also assessed. The coverage rate for two doses of rotavirus vaccination was 92.2% (95% confidence interval: 90.2-93.8). Respectively 31.7% and 10.1% of the children received their first and second dose at the recommended age. Incomplete vaccination was often a deliberate choice of the parents. Only eight children (1%) were vaccinated after the maximum age of 26 weeks. Factors identified by multiple logistic regression as related to incomplete vaccination were: living in the province of Antwerp, unemployed mother, and three or more older siblings in the household. Four years after introduction, the coverage rates were surprisingly high for a vaccine that is not fully reimbursed and not readily available in the vaccinator's fridge, which is the case for the other recommended infant vaccines.

show abstract

Section: Resultsmentioning

confidence: 99%

Rotavirus vaccination coverage and adherence to recommended age among infants in Flanders (Belgium) in 2012

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Five common serotypes (G1, G2, G3, G4, and G9) are responsible for over 98% of all RV infections in Europe [4]. Studies on RV genotype distribution are very few in Greece, although some remarkable works have recently been published [3,18]. During a multicenter study conducted during the period 2007-2008, a strain that displayed the unusual G12P[14] type was finally identified as G8P[14] [3].…”

Section: Figmentioning

confidence: 99%

Rare Types of Rotaviruses Isolated from Children with Acute Gastroenteritis in Patras, Greece

et al. 2013

View full text Add to dashboard Cite

Background: Acute diarrhea remains a major public health issue worldwide, with gastroenteritis agents associated with a high morbidity, especially in infants and young children. A 1-year study (2009-2010) of rotavirus (RV)-caused pediatric diarrhea was performed on hospitalized children admitted with symptoms of acute diarrhea to the University Hospital of Patras, Greece. Methods: Twenty-nine fecal samples were investigated for RVs, adenoviruses (AdVs), and enteroviruses (EVs) in an attempt to characterize these enteric viruses, which have been implicated in hospitalized diarrhea. Results: A 44.8% (13/29) incidence of viral infection was reported for the viral targets. Monoinfections accounted for 31% (9/29), while bi-infections accounted for 13.4% (4/29). Sequencing of positive samples allowed identification of RVs G4P[8] (2/29), G9P[8] (1/29), and interestingly of the rare type G12P[8] (2/29). AdV types 1, 2, and 6 were also identified in 4/29, 1/29, and 1/29 of the samples, respectively. Regarding the EVs, EV71 (2/29), coxsackievirus A4 (1/29), echovirus 11 (1/29), and EV96 (1/29) were typed. Conclusion: The results of the present study, and specifically the detection of rare RV G12 and EV71 strains, address the need for continuous epidemiological surveys to provide epidemiological pictures of pediatric viral infections circulating in the community.

show abstract

“…Rotavirus and norovirus were detected in 28.6% patients and 18.1% patients in our hospital, respectively [16]. Most infants acquire rotavirus diarrhea early in life; an effective rotavirus vaccine would have a major effect on reducing diarrhea mortality [17][18][19][20][21][22][23][24]. The introduction of rotavirus vaccines in infants should be considered to reduce severe diarrhea and admission for the disease burden of the major cause of severe childhood gastroenteritis in the past and recent years in our study.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2016

JPNC

View full text Add to dashboard Cite

Hospital-based surveillance of rotavirus gastroenteritis in the era of limited vaccine uptake through the private sector

Cited by 24 publications

References 19 publications

Rotavirus vaccination coverage and adherence to recommended age among infants in Flanders (Belgium) in 2012

Rotavirus vaccination coverage and adherence to recommended age among infants in Flanders (Belgium) in 2012

Rare Types of Rotaviruses Isolated from Children with Acute Gastroenteritis in Patras, Greece

Untitled

Contact Info

Product

Resources

About