Hospital‐based prevalence of high‐risk cervical HPV types infecting the general population and female sex workers in Huzhou, China

Wang, Xiang; Gu, Donghua; Liu, Bin; Xu, Bin; Qian, Fuchu; Chen, Yu

doi:10.1016/j.ijgo.2012.07.019

Cited by 10 publications

(10 citation statements)

References 29 publications

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“…The prevalence and distribution of HPV genotypes vary greatly around the world; the differences could be related to the complex interaction between the different types of HPV and biological characteristics, in addition to the geographic location of the study population [20]. A recent review conducted in 11 countries in South America, Europe, and Asia (Nigeria, India, Vietnam, Thailand, South Korea, Colombia, Argentina, Chile, the Netherlands, Italy and Spain) [21], comprising 15 613 women aged 15-74 years, found that the most common genotypes among these countries were HPV16, HPV42, HPV58, HPV31, HPV18, HPV56, HPV81, HPV35, HPV33, and HPV45.…”

Section: Discussionmentioning

confidence: 99%

Human papillomavirus among women with atypical squamous cells of undetermined significance in southern Brazil

Paesi¹,

Corrêa²,

Tregnago³

et al. 2014

Intl J Gynecology & Obste

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Section: Discussionmentioning

confidence: 99%

Human papillomavirus among women with atypical squamous cells of undetermined significance in southern Brazil

Paesi¹,

Corrêa²,

Tregnago³

et al. 2014

Intl J Gynecology & Obste

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“…Along with cervical cancer, HPV types 16 and 18 are responsible for 40%-50% of invasive vulvar cancer and 70% of vaginal cancer [3]. 18,31,33,35,39,45,51,52,56,58,59, 66, 68, 73 and 82 are considered high risk genotypes, whereas low-risk genotypes include HPV- 6,11,34,40,42,43,44,54,61,70,72,81, and 89 [4]. There are three available HPV vaccines licensed by the U.S. Food and Drug Administration (FDA): quadrivalent HPV vaccine, including HPV types 6,11,16 and 18 (Gardasil®, produced by Merck); bivalent HPV vaccine, including HPV types 16 and 18 (Cervarix™, produced by GlaxoSmithKline), and nine-valent vaccine, including HPV types 6,11,16,18,31,33,45,52 and 58 (Gardasil 9; produced by Merck) [5,6].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

Farahmand

Moghoofei

Dorost

et al. 2020

Preprint

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Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and the distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-two studies involving 21402 FSWs from 33 countries were included in this meta-analysis, and the pooled HPV prevalence was 42.60% (95% confidence interval (CI): 38.58%-46.71%). HPV-16 (10.16%, 95% CI: 8.20%–12.51%), HPV-52 (7.98%, 95% CI: 5.91%–10.70%), and HPV-53 (6.01%, 95% CI: 4.40%–8.15%) were the most common high-risk HPV types identified among FSWs. The pooled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.64% (95% CI: 36.12%-51.46%) and 41.97% (95% CI: 37.28%-46.81%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and the incidence of HPV-associated malignancies among the general population.

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“…To date, no reports are available on the HPV infection and cervical dysplasia in FSWs in Shenyang, Liaoning, a province in Northeast China. Moreover, risk factors for HPV infection in FSWs in Shenyang have not been well defined, although the association of HPV infection with various demographic and behavioral variables has been assessed in FSWs in other studies [ 9 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

Human papillomavirus infection and cervical dysplasia in female sex workers in Northeast China: an observational study

et al. 2015

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BackgroundWomen having multiple sex partners are reportedly at an increased risk of HPV infection. However, the prevalence and risk factors of HPV infection in female sex workers (FSWs) vary considerably across racial/ethnic, socioeconomic, and geographic groups. This study aimed to determine the prevalence and risk factors of HPV infection in FSWs in Northeast China.MethodsA total of 309 FSWs identified and approached through a local police office and 1000 healthy subjects from a single factor undergoing annual gynecological examinations in Shenyang were recruited. A liquid-based ThinPrep Pap test and the Hybrid Capture II-based high-risk HPV DNA test, with or without a colposcopic examination, were performed on both FSWs and control subjects. Data on HPV infection and histological and cytological lesions of the cervix were obtained and analyzed. A questionnaire survey was administered to all 309 FSWs with their socio-demographic and behavioral information collected. The association of various socio-demographic and behavioral variables with HPV infection was assessed.ResultsHPV was significantly more prevalent in FSWs (61.90 %) than in healthy control subjects (21.00 %) (P < 0.01), so were cervical lesions (P < 0.01). HPV prevalence in our sample of FSWs fell in the upper range of reported values in FSWs across different countries, and was similar to that for FSWs in the southeast Chinese city of Huzhou but higher than that for FSWs in southwest China, Guangxi, as compared with data from other studies within China. HPV infection in FSWs was significantly associated with the age at first sexual intercourse (OR 0.699, 95 % CI 0.492–0.992) and post-menopause (OR 2.928, 95 % CI 1.099–7.800) (P < 0.05).ConclusionsFSWs are at a substantially high risk of HPV infection and cervical dysplasia development as compared with healthy control subjects in Shenyang, China. Age of first sexual intercourse and post-menopause are two independent risk factors for HPV infection in this special group of population. Intensified and coordinated efforts from government, public health sector, communities and families are needed to reduce the risk of HPV infection in this specific group of population.

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Hospital‐based prevalence of high‐risk cervical HPV types infecting the general population and female sex workers in Huzhou, China

Abstract: Female sex workers in Huzhou, China, were found to have a greater probability of being infected with high-risk HPV, and novel vaccines against HPV-58 and HPV-52 should be developed. Using condoms could reduce the risk of infection.

Cited by 10 publications

References 29 publications

Human papillomavirus among women with atypical squamous cells of undetermined significance in southern Brazil

Human papillomavirus among women with atypical squamous cells of undetermined significance in southern Brazil

Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

Human papillomavirus infection and cervical dysplasia in female sex workers in Northeast China: an observational study

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