Hospital admission trends due to respiratory diseases in England and Wales between 1999 and 2019: an ecologic study

Naser, Abdallah Y; Mansour, Munthir; Alanazi, Abeer F. R.; Sabha, Omar; Alwafi, Hassan; Jalal, Zahraa; Paudyal, Vibhu; Dairi, Mohammad S; Salawati, Emad; Alqahtan, Jaber S.; Alaamri, Shalan; Ali, Muhamad

doi:10.1186/s12890-021-01736-8

Cited by 29 publications

(26 citation statements)

References 35 publications

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“…Previous studies in Denmark, Sweden, and Norway explored the utilisation pattern of different classes of medications such as opioids and antiarrhythmic medications and reported an increase in their utilisation [ 33 – 35 ]. Recent studies in the UK showed an increase in hospitalizations for various acute and chronic conditions, such as viral diseases, respiratory diseases, and heart diseases [ 19 , 36 , 37 ]. Raised hospitalisation rates highlight that there is an increase in the prevalence of these diseases that lead to hospitalisation, which itself could lead to an increase in the prescribing pattern of medications.…”

Section: Discussionmentioning

confidence: 99%

Drugs utilization profile in England and Wales in the past 15 years: a secular trend analysis

et al. 2022

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Background Medication use assessment has a critical role in promoting the effective and rational use of pharmaceutical medications. There are no studies that have explored the utilization of all medications in England and Wales in the past 15 years without restrictions in the age group being studied or class of medications. Aim To explore the medication utilization pattern of dispensed medications in England and Wales in the past 15 years. Method A secular trend analysis study using publically available dispensing data on the population level in England and Wales for the duration between 2004 and 2019. Medication dispensing data was extracted from the Prescription Cost Analysis database. Results Medication prescriptions rate increased by 42.6% [from 1,345,095.75 (95% CI 1,345,004.25 – 1,345,187.26) in 2004 to 1,918,138.48 (95% CI 1,918,038.38 – 1,918,238.57) in 2019 per 100,000 persons, trend test, p < 0.001]. During the study period, the most common medication prescriptions were for the cardiovascular system, central nervous system, and endocrine system, which accounted for 30.2%, 18.8%, and 9.4%, respectively. The rate of medication prescriptions for skin, immunological products and vaccines, infections, and musculoskeletal and joint diseases decreased by 18.4%, 15.8%, 9.8%, and 5.7%, respectively. Conclusion The last two decades have witnessed a remarkable rise in the quantity of medications dispensed in community settings. Utilization of chronic disease medications has increased in the past 15 years, specifically, dispensed medications for the cardiovascular system, central nervous system, and endocrine system. It is necessary to conduct additional cohort studies to investigate the clinical outcomes and prescribing safety of these medications. Supplementary Information The online version contains supplementary material available at 10.1186/s12875-022-01853-1.

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Section: Discussionmentioning

confidence: 99%

Drugs utilization profile in England and Wales in the past 15 years: a secular trend analysis

et al. 2022

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“…The HES database provides detailed information on hospital admissions associated with a wide range of health conditions in England, and the PEDW provides similar information related to Wales residents [13][14][15][16][17][18][19]. The HES database's patient admitted care data includes all NHS-paid admissions to private or nonprofit hospitals.…”

Section: Data Sources and Study Populationmentioning

confidence: 99%

“…Considering age group variations in NRHA, the age group 60-74 years accounted for 38.5% of the total number of NRHA, followed by the 15 2).…”

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confidence: 99%

Trends in Hospital Admissions Due to Neoplasms in England and Wales between 1999 and 2019: An Ecological Study

Naser

Alwafi

Hemmo

et al. 2022

IJERPH

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Objectives: This study aimed to investigate the trends in neoplasm-related hospital admissions (NRHA) in England and Wales between 1999 and 2019. Methods: This is an ecological study using publicly available data taken from the two main medical databases in England and Wales; the Hospital Episode Statistics database in England and the Patient Episode Database in Wales. Hospital admissions data were collected for the period between April 1999 and March 2019. Results: A total of 35,704,781 NRHA were reported during the study period. Females contributed to 50.8% of NRHA. The NRHA rate among males increased by 50.0% [from 26.62 (95% CI 26.55–26.68) in 1999 to 39.93 (95% CI 39.86–40.00) in 2019 per 1000 persons, trend test, p < 0.001]. The NRHA rate among females increased by 44.1% [from 27.25 (95% CI 27.18–27.31) in 1999 to 39.25 (95% CI 39.18–39.32) in 2019 per 1000 persons, trend test, p < 0.001]. Overall, the rate of NRHA rose by 46.2% [from 26.93 (95% CI 26.89–26.98) in 1999 to 39.39 (95% CI 39.34–39.44) in 2019 per 1000 persons, trend test, p < 0.001]. Conclusion: Hospital admission rates due to neoplasms increased between 1999 and 2019. Our study demonstrates a variation in NRHA influenced by age and gender. Further observational studies are needed to identify other factors associated with increased hospital admissions among patients with different types of neoplasms.

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“…As previously described [9][10][11], we conducted an ecological study using publicly available data extracted from the Hospital Episode Statistics (HES) database in England and the Patient Episode Database for Wales (PEDW) between April 1999 and April 2019 [12,13]. The HES and PEDW databases contain hospital admission data for patients with B&ID from all age groups, which are subdivided into four categories -below 15 years, 15-59 years, 60-74 years, and 75 years and above.…”

Section: Study Sources and The Populationmentioning

confidence: 99%

Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales

Ali¹,

Naser²,

AbuAlhommos³

et al. 2022

Cureus

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BackgroundNon-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) category diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (B&ID). MethodsWe conducted an ecologic study to analyze hospital admission data obtained from England's Hospital Episode Statistics database and Wales' Patient Episode Database. Hospital admissions data for nonmalignant hematologic disorders and immune disorders were extracted for the period from April 1999 to March 2019. We used the Poisson model to assess trends in hospital admissions. ResultsThe total annual B&ID-related hospital admission (RHA) rate for all categories increased by 137.9% between 1999 and 2019 (p<0.01). Females accounted for 54% of all B&ID-RHA. Around 37% of B&ID-RHA were seen in the age group of 15-59 years and 29% in the age group of 75 years and above. The most common causes of B&ID-RHA were aplastic and other anemias and other bone marrow failure syndromes, ICD-10 category (33%) and nutritional anemias category (28%). Certain disorders involving the immune mechanism category accounted for the least number of B&ID-RHA (8.4%). The highest increase in B&ID-RHA was seen in the nutritional anemias category (3.86 fold), followed by certain disorders involving the immune mechanism (1.28 fold). Iron deficiency anemia accounted for 95.1% of all hospitalizations secondary to nutritional anemias. Around half of all, hemolytic anemia category hospitalizations were secondary to the sickle cell anemia subcategory. ConclusionsHospital admissions trends in non-malignant hematologic and immune disorders changed dynamically among age groups and gender in England and Wales over the last two decades. Understanding these changes has important implications for public health planning.

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Hospital admission trends due to respiratory diseases in England and Wales between 1999 and 2019: an ecologic study

Cited by 29 publications

References 35 publications

Drugs utilization profile in England and Wales in the past 15 years: a secular trend analysis

Drugs utilization profile in England and Wales in the past 15 years: a secular trend analysis

Trends in Hospital Admissions Due to Neoplasms in England and Wales between 1999 and 2019: An Ecological Study

Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales

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