Hospital-Acquired Pneumonia Associated With the Causative Agent Stenotrophomonas Maltophilia, in Newborn Infants

Кушнарева, М. В.; Marhulia, H. M.; Dementyeva, G. M.; Chursina, E. S.; Кешишян, Е. С.; Семенов, А. В.

doi:10.21508/1027-4065-2017-62-3-53-58

Cited by 1 publication

(3 citation statements)

References 8 publications

(18 reference statements)

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“…We compared the clinical course of VAP, associated with K. pneumoniae, with the VAP clinic with a different etiology that was described in previous studies [15,16]. Thus, the mixed infection was 2 times less frequent met and the secondary infection was 1.8 times less frequent met in infants with VAP, associated with K. pneumoniae.…”

Section: Maternal Healthmentioning

confidence: 95%

“…However, there was no lethal in the presence of VAP, associated with Sten. maltophilia [16]. Sepsis was developed with infection caused by P. aeruginosa (in 6% of infants) and Sten.…”

Section: Maternal Healthmentioning

confidence: 99%

“…maltophilia (13%). In addition, there was a tendency to a longer period of toxicosis (5 and 6 days in average, respectively) and a severe condition of the patients (4 and 5 days in average, respectively), and renal dysfunction (in 29 and 67% infants, respectively) with these VAP pathogens [15,16]. Hemorrhagic syndrome was developed in 29% of infants in VAP, caused by P. aeruginosa [15].…”

Section: Maternal Healthmentioning

confidence: 99%

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Ventilator-Associated Pneumonia Caused by Klebsiella Pneumoniae in Preterm Newborn Infants

Mv¹,

Kh²,

Keshishyan³

et al. 2018

Int J Pediatr Res

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Background: The basis for the study is the high morbidity and mortality in premature infants with ventilator-associated pneumonia (VAP). There is a high incidence of complications (sepsis, bronchopulmonary dysplasia). Methods: A detailed analysis of the clinical course of VAP caused by Klebsiella pneumoniae in 14 premature infants was conducted. The sensitivity of Klebsiella pneumoniae strains to 18 antibiotics was studied by the method of standard discs. Results: Severe pneumonia had 10 infants, moderate stage was among 4 infants, an acute stage was observed in 12 patients, and prolonged stage was in 2 infants. Severe form of the disease was presented by pronounced symptoms of infectious toxicosis, respiratory and cardiovascular insufficiency, physical changes from the lungs. Bronchopulmonary dysplasia was developed in two infants. The mortality was rated 14%. Klebsiella pneumoniae was the causative agent of the primary infection in all infants (monoinfection was in 12 infants and association with other pathogens in 2 infants). All strains of Klebsiella pneumoniae were multidrug-resistant to antibiotics, but 57-86% of the strains retained sensitivity to Piperacillin, Piperacillin + Tazobactam, carbapenems, Amikacin and Ofloxacin. Conclusions: The complex treatment of VAP in premature infants should include antibacterial, detoxification, pathogenetic and syndromic therapies.

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Section: Maternal Healthmentioning

confidence: 95%

“…However, there was no lethal in the presence of VAP, associated with Sten. maltophilia [16]. Sepsis was developed with infection caused by P. aeruginosa (in 6% of infants) and Sten.…”

Section: Maternal Healthmentioning

confidence: 99%