Horse spleen segmentation technique as large animal model of preclinical trials

Abstract

The parenchymal distribution of the splenic artery was studied in order to obtain anatomical basis for partial splenectomy. Thirty two spleens were studied, 26 spleens of healthy horses weighing 320 to 450kg, aged 3 to 12 years and 6 spleens of fetus removed from slaughterhouse. The spleens were submitted to arteriography and scintigraphy in order to have their vascular pattern examined and compared to the external aspect of the organ aiming establish anatomo-surgical segments. All radiographs were photographed with a digital camera and the digital images were submitted to a measuring system for comparative analysis of areas of dorsal and ventral anatomo-surgical segments. Anatomical investigations into the angioarchitecture of the equine spleen showed a paucivascular area, which coincides with a thinner external area, allowing the organ to be divided in two anatomo-surgical segments of approximately 50% of the organ each.

Successful treatment of a splenic abscess secondary to migrant metallic wires in a horse

“…A partial splenectomy was performed in this case, which to the authors’ knowledge has not been previously reported in live equines (Foz Filho et al . 2013). The literature describes both minimally invasive and traditional surgical methods to access and remove the equine spleen.…”

“…Two anatomo‐surgical segments dividing the spleen approximately in half were characterised (Foz Filho et al . 2013). However, the splenic lesions in this colt involved close to 70% of the organ's parenchyma.…”

“…However, the published anatomo‐surgical segments (Foz Filho et al . 2013) could not be used, and, following ligation of the arcuate splenic vessels and stapling of the spleen parenchyma with a linear stapler (ILA 100), the affected 70% of the spleen was removed ( Fig 1). This procedure seems justifiable as a surgical option for splenic masses to preserve as much of the organ's function (i.e.…”

“…However, despite the advantages of salvaging splenic tissue, the minimum mass of normal splenic tissue capable of maintaining an adequate immune system still remains undefined and patients must be monitored closely for signs of septicaemia into the future (Foz Filho et al . 2013).…”

Splenic abscessation: Is partial splenectomy a treatment option?

“…A study of the angioarchitecture of the normal equine spleen as an anatomical basis for partial splenectomy has also been documented (Foz Filho et al . 2013). However, splenic abscesses are usually associated with extensive adhesions to the body wall and associated intra‐abdominal organs, including the intestinal tract.…”