Horner's syndrome: an atypical presentation in a child with neurofibromatosis type 2

Abstract

Figure 1 Thoracic MRI showing an intraspinal/thoracic tumour with an extension from CVI to ThII and extrapleurally left side (with permission of the patient).Correspondence

Horner’s syndrome, Pseudo-Horner’s syndrome, and simple anisocoria

“…Paraxial tumors, such as neuroblastoma in children, can present with Horner's syndrome from primary or metastatic disease involving the sympathetic chain in the neck or thorax. Preganglionic Horner's syndrome has been described as the presenting sign of neurofibromatosis type I, secondary to a malignant peripheral nerve sheath tumor at the base of the neck [11], and also in neurofibromatosis type II, secondary to an intrathoracic neurofibroma [12]. Other recently reported mediastinal or intrathoracic lesions causing Horner's syndrome include hydatid cyst [13], malignant vagus nerve schwannoma [14], thoracic endometriosis [15], pulmonary mucormycosis [16,17].…”