We consider the quantization of space-times which can possess different topologies within a symmetry reduced version of Wheeler-DeWitt theory. The quantum states are defined from a natural decomposition as an outer-product of a topological state, dictating the topology of the two-surfaces of the space-time, and a geometric state, which controls the geometry and is comprised of solutions to the Wheeler-DeWitt constraints. Within this symmetry reduced theory an eigenvalue equation is derived for the two-volume of spacetime, which for spherical topology is fixed to a value of 4π. However, for the other topologies it is found that the spectrum can be discrete and hence the universe, if in one of these other topological states, may only possess certain possible values for the two-volume, whereas classically all values are allowed. We analyze this result in the context of pure gravity (black holes).