Hormonal Response in Sepsis

Growth hormone and insulin‐like growth factor 1 levels and their relation to survival in children with bacterial sepsis and septic shock

“…If not recognized and treated early, sepsis can progress to severe sepsis, septic shock and multiple organ dysfunction syndrome, and death. Despite improved supportive care, mortality from sepsis and septic shock is still high 1 .…”

“…In critically ill adult patients, especially those with sepsis, septic shock, burns, major surgery and multiple organ trauma, many endocrine systems are disrupted 1 . Important among these is the complex system interrelating growth hormone (GH), the insulin‐like growth factors (IGF) and the insulin‐like growth factor‐binding proteins (IGFBP) 2,3 .…”