“…'4C02 release from [1-'4C]pyruvate has been used, e.g. in the perfused rat liver (Haussinger et al, 1975;Scholz et al, 1978;Patel et al, 1982;Zwiebel et al, 1982;Sies et al, 1983), heart (Hiltunen & Hassinen, 1976;Dennis et al, 1979;Waymack et al, 1979;Bunger et al, 1983), and skeletal muscle (Schadewaldt et al, 1983b,c) (Jungas, 1971; for further references see Denton & Hughes, 1978) and the lactating mammary gland (Kankel & Reinauer, 1976;Baxter & Coore, 1978). Contradictory results have been reported for the rat heart (Kerbey et al, 1976;Ohlen et al, 1978) and liver (Patzelt et al, 1973;Topping et al, 1977 Hennig et al (1975), and studies on the putative intracellular mediator of insulin (Jarett & Seals, 1979;Larner et al, 1979) (Hansford & Cohen, 1978;Dennis et al, 1979;Waymack et al, 1979;Bunger et al, 1983).…”