Hormonal parameters following termination of pregnancy: A guide to the management of threatened abortion

Saunders, Douglas M.; Kelso, Ian

doi:10.1016/0002-9378(74)90161-6

Cited by 7 publications

(5 citation statements)

References 2 publications

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“…Our results were not corrected for extraction losses, which means 10-15% in results. After abortion, a rapid decline in progesterone concentration was observed as has been reported earlier (Holmdahl et al, 1971;Saunders & Kelso, 1974). An interesting increase of short duration in progesterone concentration in plasma was observed between days 6 and 13 after abortion.…”

Section: Discussionsupporting

confidence: 79%

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Return of Ovarian Function After Abortion

Lähteenmäki

Luukkainen

1978

Clinical Endocrinology

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The first menstrual cycle after a therapeutic abortion was studied in eighteen women by measuring plasma oestradiol and progesterone concentrations and the urinary excretion of LH until the first menstruation. The plasma concentrations of oestradiol and progesterone declined rapidly, reaching low values as early as the second day after the abortion. An increase in plasma oestradiol levels was observed from the seventh post-abortal day onwards. P peak of short duration in the plasma progesterone concentrations occurred during the increased oestradiol synthesis. The concentration of progesterone during the luteal phase of the cycle was lower than in a normal cycle, indicating an inadequate luteal function. Return of ovulation was observed in 83% of patients during the first cycle; as judged by a biphasic oestradiol profile in plasma, a mid-cycle LH peak, and subsequent elevation of progesterone. The first LH peak was observed 16 days after the abortion. The rapid return of the ovulatory function makes immediate post-abortal contraception a necessity.

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Section: Discussionsupporting

confidence: 79%

“…Plasma progesterone was also measured by a direct radioimmunoassay after petroleum ether (b.p. 40-60°C) extraction, as described by Thorneycroft & Stone (1972). [ 1 ,2,6,7-3H] progesterone (84 Ci/mmol), Radiochemical Centre, Amersham, U.K.) was used as a label.…”

Section: Hormone Assaysmentioning

confidence: 99%

Return of Ovarian Function After Abortion

Lähteenmäki

Luukkainen

1978

Clinical Endocrinology

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“…The state of the pituitary-ovarian axis in the immediate postabortal period is poorly understood; most studies are short-term, and limited to the first few days after abortion [7][8][9]. These studies provide information about the dynamics of some hormones in the immediate postabortal period, but lack information about recovery of the pituitary-ovarian axis and reproductive performance.…”

Section: Discussionmentioning

confidence: 97%

Sequential hormone measurements after first trimester abortion in normal Nigerian women

Osotimehin¹,

Otolorin

Ladipo

1985

Adv Contracept

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This study looks at the dynamics of the pituitary hormones and progesterone in normal adult Nigerian females during their first postabortal cycle. Serial determinations of serum concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PrL) and progesterone were carried out on eleven normal Nigerian women during the first postabortal period after menstrual regulation. Nine out of the eleven subjects (82%) attained LH peaks within the first 22 days after menstrual regulation, seven had discernible FSH peaks and seven had serum progesterone concentrations greater than 6 nmol/l during the second half of the study period. Subjects probably ovulated during the first postabortal cycle; serial LH seems to be the most reliable index of ovulation in our subjects. We hope these data will aid in development of effective family planning strategies for women in the first postabortal cycle.

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“…The elimination of progesterone was even more rapid after abortions conducted during weeks 12-16 of pregnancy. Saunders and Kelso (1974) measured plasma progesterone concentrations 6 days after the termination of pregnancy at 8 to 20 weeks, and mean plasma progesterone concentrations were seen to fall from 15.9 ng/ml to 1.9 nglml within 24 hours.…”

Section: Disappearance Of Estradiol Progesterone and Human Chorionicmentioning

confidence: 99%

“…After 48 hours, about 5-15 O/o of the original concentration of HCG remained in the blood. Saunders and Kelso (1974) studied 'the postabortal occurrence of HCG in urine by a commercial pregnancy test. Five days after abortion 59 O/o of the tests were negative.…”

Section: Disappearance Of Estradiol Progesterone and Human Chorionicmentioning

confidence: 99%

Influence of Oral Contraceptives on Immediate Postabortal Pituitary‐Ovarian Function

Lähteenmäki

1978

Acta Obstet Gynecol Scand

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Hormonal parameters following termination of pregnancy: A guide to the management of threatened abortion

Cited by 7 publications

References 2 publications

Return of Ovarian Function After Abortion

Return of Ovarian Function After Abortion

Sequential hormone measurements after first trimester abortion in normal Nigerian women

Influence of Oral Contraceptives on Immediate Postabortal Pituitary‐Ovarian Function

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