2018
DOI: 10.1016/j.cps.2018.03.003
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Hormonal Management for Transfeminine Individuals

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Cited by 7 publications
(7 citation statements)
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“…This should be initiated in adolescents once they reach their adult dose of estradiol. In the United States, spironolactone is used most commonly (Abramowitz, 2019;Abramowitz & Tangpricha, 2018). Spironolactone inhibits testosterone α secretion, blocks androgen receptor binding, and may also have estrogenic activity (Hembree et al, 2017).…”
Section: Transgender Womenmentioning
confidence: 99%
“…This should be initiated in adolescents once they reach their adult dose of estradiol. In the United States, spironolactone is used most commonly (Abramowitz, 2019;Abramowitz & Tangpricha, 2018). Spironolactone inhibits testosterone α secretion, blocks androgen receptor binding, and may also have estrogenic activity (Hembree et al, 2017).…”
Section: Transgender Womenmentioning
confidence: 99%
“…19 Various forms of fertility preservation exist (i.e., testicular sperm extraction and banking, oocyte harvesting and banking, and ovarian tissue cryoprecipitation) and should be discussed with individuals before starting therapies that may affect fertility. 19,21,22 Feminizing treatments and practices: Hormone therapy for trans women and transfeminine people typically includes an estrogen and antiandrogen (such as spironolactone), and may also include a progestin. Estrogen therapy will induce breast tissue development.…”
Section: Creating a Respectful Health Care Environmentmentioning
confidence: 99%
“…Estrogen therapy will induce breast tissue development. 21,23,24 There is one case report and many anecdotal reports of trans women inducing lactation (see Induced Lactation and Colactation section) and producing human milk. Breast augmentation in trans women may mask inadequate mammary tissue development or result in pressure atrophy of remaining tissue.…”
Section: Creating a Respectful Health Care Environmentmentioning
confidence: 99%
“…As stated before, exogenous hormones should be taken for 1 to 2 years in order to maximize growth of native tissue in preparation for surgical augmentation (8). The most common type of exogenous hormone involves 17-β estradiol, which is often taken orally in doses of 2 to 6 mg per day, but anti-androgens and other formulations are also commonly used (14). Exogenous estrogens may be stopped 2-4 weeks preceding surgery to reduce risk of thromboembolism (15).…”
Section: Preoperative Planningmentioning
confidence: 99%