Hormonal dynamics reveal a stimulatory role for secretoneurin in zebrafish ovulation
Di Peng,
Chunyu Lu,
Victoria Spadacini
et al.
Abstract:Surge release of luteinizing hormone (Lh) from the pituitary is essential for fertility as it triggers ovulation. While secretoneurin (SN) is a phylogenetically conserved secretogranin-2 derived peptide that stimulates Lh, its role in ovulation has not been established. To directly compare periovulatory changes in the classical hormones to the emerging reproductive neuropeptides SNa and SNb, simultaneous mass spectrometry measurement of 9 peptides and 5 steroids was conducted in female zebrafish. Regression an… Show more
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