HOP3 a new regulator of the ER stress response in Arabidopsis with possible implications in plant development and response to biotic and abiotic stresses

Fernández-Bautista, Nuria; Fernández‐Calvino, Lourdes; Muñoz, Alfonso; Castellano, M. Mar

doi:10.1080/15592324.2017.1317421

Cited by 9 publications

(6 citation statements)

References 32 publications

(24 reference statements)

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“…The application of acetic acid increased the expression of various stress response and stress tolerance-related genes, such as heat shock family proteins, HSP20 (Muthusamy et al, 2017), HSP21 (Zhong et al, 2013), HSP70 (Tang et al, 2016; Leng et al, 2017) and HSP90 (Krishna and Gloor, 2001), ER stress-related gene, HOP3 (At4g12400; Fernández-Bautista et al, 2017a,b), catalase 1 and catalase 2 (Zou et al, 2015), multiprotein-bridging factor 1c gene ( MBF1c ; Alavilli et al, 2017), and an outer membrane tryptophan-rich sensory protein (TSPO) (Guillaumot et al, 2009). HSP20 and HSP70 family members function as molecular chaperones and help plants adapt to environmental stress (Tang et al, 2016; Leng et al, 2017; Muthusamy et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

“…HSP21 is involved in the protection against oxidative stress (Zhong et al, 2013). HOP3, a member of the HOPs [heat shock protein 70 (HSP70) and heat shock protein 90 (HSP90) organizing proteins] family in Arabidopsis plays an essential role in the response of the endoplasmic reticulum (ER) in plants to abiotic stress (Fernández-Bautista et al, 2017a). HOP3 has been suggested, through its role in the alleviation of ER stress, to play an important function in plant response to various stresses (Fernández-Bautista et al, 2017a).…”

Section: Discussionmentioning

confidence: 99%

“…HOP3, a member of the HOPs [heat shock protein 70 (HSP70) and heat shock protein 90 (HSP90) organizing proteins] family in Arabidopsis plays an essential role in the response of the endoplasmic reticulum (ER) in plants to abiotic stress (Fernández-Bautista et al, 2017a). HOP3 has been suggested, through its role in the alleviation of ER stress, to play an important function in plant response to various stresses (Fernández-Bautista et al, 2017a). It is plausible to suggest that acetic acid treatment enhances drought avoidance in cassava through the regulation of the ER stress response.…”

Section: Discussionmentioning

confidence: 99%

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Acetic Acid Treatment Enhances Drought Avoidance in Cassava (Manihot esculenta Crantz)

Utsumi

Tanaka

et al. 2019

Front. Plant Sci.

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The external application of acetic acid has recently been reported to enhance survival of drought in plants such as Arabidopsis , rapeseed, maize, rice, and wheat, but the effects of acetic acid application on increased drought tolerance in woody plants such as a tropical crop “cassava” remain elusive. A molecular understanding of acetic acid-induced drought avoidance in cassava will contribute to the development of technology that can be used to enhance drought tolerance, without resorting to transgenic technology or advancements in cassava cultivation. In the present study, morphological, physiological, and molecular responses to drought were analyzed in cassava after treatment with acetic acid. Results indicated that the acetic acid-treated cassava plants had a higher level of drought avoidance than water-treated, control plants. Specifically, higher leaf relative water content, and chlorophyll and carotenoid levels were observed as soils dried out during the drought treatment. Leaf temperatures in acetic acid-treated cassava plants were higher relative to leaves on plants pretreated with water and an increase of ABA content was observed in leaves of acetic acid-treated plants, suggesting that stomatal conductance and the transpiration rate in leaves of acetic acid-treated plants decreased to maintain relative water contents and to avoid drought. Transcriptome analysis revealed that acetic acid treatment increased the expression of ABA signaling-related genes, such as OPEN STOMATA 1 (OST1) and protein phosphatase 2C ; as well as the drought response and tolerance-related genes, such as the outer membrane tryptophan-rich sensory protein (TSPO) , and the heat shock proteins . Collectively, the external application of acetic acid enhances drought avoidance in cassava through the upregulation of ABA signaling pathway genes and several stress responses- and tolerance-related genes. These data support the idea that adjustments of the acetic acid application to plants is useful to enhance drought tolerance, to minimize the growth inhibition in the agricultural field.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Acetic Acid Treatment Enhances Drought Avoidance in Cassava (Manihot esculenta Crantz)

Utsumi

Tanaka

et al. 2019

Front. Plant Sci.

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“…HSPs (e.g., HSP90) maintain the tridimensional integrity of proteins including membrane and cytosolic receptors and transductors of pathogenic signals (e.g., RPM1), ( Hubert et al., 2003 ; Park et al., 2015 ). Complexes including cochaperones (HOP3) and HPS70 and HSP90 may be key to allowing correct protein folding in the ER during periods of high abiotic or biotic stress ( Fernández-Bautista et al., 2017 ). The activation of these genes in the moderately resistant genotype (‘Laurentian’) is notable since, to our knowledge, there are only two reports of regulation of HSPs in this pathosystem ( Zhao et al., 2017 ; Luo et al., 2018 ).…”

Section: Contrasting and Shared Gene Expression Leads To Clues Regardmentioning

confidence: 99%

Response of Brassica napus to Plasmodiophora brassicae Involves Salicylic Acid-Mediated Immunity: An RNA-Seq-Based Study

et al. 2020

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Clubroot, caused by the obligate parasite Plasmodiophora brassicae , is an important disease of the Brassicaceae and poses a significant threat to the $26.7 billion canola/oilseed rape ( Brassica napus ) industry in western Canada. While clubroot is managed most effectively by planting resistant host varieties, new pathotypes of P. brassicae have emerged recently that can overcome this resistance. Whole genome analyses provide both a toolbox and a systemic view of molecular mechanisms in host-pathogen interactions, which can be used to design new breeding strategies to increase P. brassicae resistance. We used RNA-seq to evaluate differential gene expression at 7, 14 and 21 days after inoculation (dai) of two B. napus genotypes with differential responses to P. brassicae pathotype 5X. Gall development was evident at 14 dai in the susceptible genotype (the oilseed rape ‘Brutor’), while gall development in the resistant genotype (the rutabaga ( B. napus ) ‘Laurentian’) was limited and not visible until 21 dai. Immune responses were better sustained through the time-course in ‘Laurentian’, and numerous genes from immune-related functional categories were associated with salicylic acid (SA)-mediated responses. Jasmonic acid (JA)-mediated responses seemed to be mostly inhibited, especially in the resistant genotype. The upregulation of standard defense-related proteins, like chitinases and thaumatins, was evident in ‘Laurentian’. The enrichment, in both host genotypes, of functional categories for syncytium formation and response to nematodes indicated that cell enlargement during P. brassicae infection, and the metabolic processes therein, share similarities with the response to infection by nematodes that produce similar anatomical symptoms. An analysis of shared genes between the two genotypes at different time-points, confirmed that the nematode-like responses occurred earlier for ‘Brutor’, along with cell metabolism and growth changes. Additionally, the susceptible cultivar turned off defense mechanisms earlier than ‘Laurentian’. Collectively, this study showed the importance of SA in triggering immune responses and suggested some key resistance and susceptibility factors that can be used in future studies for resistance breeding through gene-editing approaches.

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“…During these processes, the demand for folding of these membrane and secreted proteins overcomes the basal folding capacity of the ER, prompting the so-called ER stress (Deng et al, 2013;Liu and Howell, 2016). In this regard, the involvement of AtHOP3 in the alleviation of the ER opens the possibility that HOP3 may also participate in processes that course with an intrinsic ER stress (Fernandez-Bautista et al, 2017b). As it seems to be the case of pollen germination in Arabidopsis (Fernandez-Bautista et al, 2017a).…”

Section: Hop Function In Plants Is Currentlymentioning

confidence: 99%

HOP, a Co-chaperone Involved in Response to Stress in Plants

et al. 2020

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Protein folding is an essential step for protein functionality. In eukaryotes this process is carried out by multiple chaperones that act in a cooperative manner to maintain the proteome homeostasis. Some of these chaperones are assisted during protein folding by different co-chaperones. One of these co-chaperones is HOP, the HSP70-HSP90 organizing protein. This assistant protein, due to its importance, has been deeply analyzed in other eukaryotes, but its function has only recently started to be envisaged in plants. In this kingdom, the role of HOP has been associated to plant response to different cellular, biotic and abiotic stresses. In this article, we analyze the current knowledge about HOP in eukaryotes, paying a special attention to the recently described roles of HOP in plants. In addition, we discuss the recent breakthroughs in the field and the possible new avenues for the study of plant HOP proteins in the future.

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HOP3 a new regulator of the ER stress response in Arabidopsis with possible implications in plant development and response to biotic and abiotic stresses

Cited by 9 publications

References 32 publications

Acetic Acid Treatment Enhances Drought Avoidance in Cassava (Manihot esculenta Crantz)

Acetic Acid Treatment Enhances Drought Avoidance in Cassava (Manihot esculenta Crantz)

Response of Brassica napus to Plasmodiophora brassicae Involves Salicylic Acid-Mediated Immunity: An RNA-Seq-Based Study

HOP, a Co-chaperone Involved in Response to Stress in Plants

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