Hookworm‐related cutaneous larva migrans successfully treated with topical ivermectin 0.1%

Ródenas‐Herranz, Teresa; Linares‐González, Laura; Martinez‐Velez, Virginia; Ruíz‐Villaverde, Ricardo

doi:10.1111/dth.13316

Cited by 3 publications

(1 citation statement)

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“…Inconsistent results have been reported in patients treated with topical ivermectin 1% cream twice daily for two weeks [ 18 , 21 , 22 ]. Interestingly, a recent report observed eradication of HrCLM in a patient treated with a low-dose ivermectin 0.1% cream twice daily for two weeks [ 23 ]. Additionally, topical thiabendazole 10–15% ointments and albendazole may provide an alternative, albeit less potent, treatment [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Larvae Migrans Treated with a Single Dose of Ivermectin

Harrison

Lukose

Dass

et al. 2022

Case Reports in Medicine

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Hookworm-related cutaneous larva migrans (HrCLM) is a clinical diagnosis based on a history of exposure to contaminated soil and is associated with a characteristic red serpiginous lesion that migrates within the epidermis. Our patient presented with a red, tortuous migratory rash with localized pruritus on the left plantar foot of 1-month duration. He lacked recent travel history outside the southeastern United States. Upon admission, he presented with peripheral blood eosinophilia, an uncommon feature of HrCLM. A single dose of ivermectin was sufficient for treatment, and symptoms resolved within 3 days. This case highlights the increased incidence of domestically acquired hookworm infections, explores this epidemiological shift, and emphasizes relevant differential diagnoses.

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