hoodscanR: profiling single-cell neighborhoods in spatial transcriptomics data
Ning Liu,
Jarryd Martin,
Dharmesh D Bhuva
et al.
Abstract:Understanding complex cellular niches and neighborhoods are giving us new insights into tissue biology. Accurate neighborhood identification is crucial, yet existing methodologies often struggle to detect mixed neighborhoods and generate cell-specific neighborhood profiles. To address these limitations, we introduce hoodscanR, a Bioconductor package designed for neighborhood identification and downstream analyses using spatial data. Applying hoodscanR to breast and lung cancer datasets, we showcase its efficac… Show more
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