Honeycomb Atrophy on the Right Cheek

Abstract

We examined a 13-year-old girl with a ten-year history of honeycomb depressions on the right side of her face. These changes began in the middle of the cheekand extended to involve a large area between the ear and the lower lip. The patient denied preceding inflammation. There were no other cutaneous lesions or systemic complaints. There was no family history of a similar condition. Figure 1.On physical examination, the patient showed extensive, unilateral honeycomb scars, irregular in shape, about 1 to 3 mm in depth and 1 to 5 mm in size. The lesions were separated from each other by narrow ridges of normal-appearing skin. There were many small comedones and milia in the depressed areas (Fig 1).A 4-mm punch biopsy specimen was taken from a representative area and is shown in Figs 2 and 3. Figure 2. HISTOPATHOLOGIC FINDINGSThe biopsy specimen showed follicular plugging with perivascular infiltration of mononuclear cells in the papillary dermis. Fibroblast proliferation and focal calcification was also evident (Fig 2). On higher magnification, extensive follicular plugging and double comedo formation can be seen (Fig 3).

Atrophodermia vermiculata: case report and review of the literature

“…Additional features of atrophodermia vermiculata may include variable degrees of inflammation and the presence of milia. Although atrophodermia vermiculata usually shows symmetrical distribution, rare unilateral variants have been decribed 5,6 . In a unique case, unilateral atrophodermia vermiculata was arranged in a linear pattern 7 .…”

“…Although atrophodermia vermiculata usually shows symmetrical distribution, rare unilateral variants have been decribed. 5,6 In a unique case, unilateral atrophodermia vermiculata was arranged in a linear pattern. 7 The described condition could represent a mosaic expression of atrophodermia vermiculata, which is usually inherited in an autosomal dominant form, due to a postzygotic mutation.…”

A case of bilateral scarring of the cheeks in a child

“…[1] The other entities in this group are Keratosis pilaris atrophicans faciei and Keratosis follicularis spinulosa decalvans. Differences in location, degree of atrophy and mode of inheritance distinguish the three entities, which are detailed in Table 1.…”

“…Rarely, the lesion may be unilateral in distribution. [13] Erythema, comedones and follicular plugs may be present. Histologic findings are as described in the case.…”

Keratosis Pilaris and Scarring Alopecia

“…Clinical features include a worm-eaten appearance of the skin on the cheeks, ears, and forehead, manifested by confluent atrophie pits separated by narrow ridges of normal-appearing skin. 6 No effective therapy is currently available for these related follicular syndromes. As these may represent disorders of keratinization of the hair follicles, therapeutic trials with syn¬ thetic retinoids may be warranted.1…”