Honey as an antimicrobial agent against Pseudomonas aeruginosa isolated from infected wounds

Shenoy, Vishnu Prasad; Ballal, Mamatha; Pg, Shivananda; Bairy, Indira

doi:10.4103/0974-777x.96770

Cited by 30 publications

(12 citation statements)

References 28 publications

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“…Shenoy et al, evaluated the antimicrobial activity of honey agent P. aeruginosa. Their results showed that all the isolates of P. aeruginosa tested were killed in 12-24 h [27]. In another study, Moussa et al, assessed the antimicrobial activity of honey against S. aureus.…”

Section: Discussionmentioning

confidence: 98%

Antibacterial Activity of Honey against Methicillin-Resistant and Sensitive Staphylococcus Aureus Isolated from Patients with Diabetic Foot Ulcer

Mirzaei¹,

Karamolah²,

Mahnaie³

et al. 2020

TOMICROJ

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Introduction: Staphylococcus aureus is the most important causative agent of wound infections, including diabetic foot ulcers. Honey is a very useful nutrient with antimicrobial properties and other biological properties such as antitumor, anti-inflammatory, antioxidant and antiviral properties. The aim was to examine the antibacterial activity of honey against methicillin-resistant and sensitive S. aureus (MRSA and MSSA) isolated from patients with diabetic foot ulcers. Methods: This cross-sectional study was performed from January 2019 to December 2019. Twenty S. aureus isolates were collected from patients with diabetic foot ulcers. Different concentrations (100%, 70%, 50%, 25% vol/vol) of honey were studied. Dilutions of honey solutions were examined to determine the minimum inhibitory concentration (MIC) against S. aureus. MICs were determined by spectrophotometric assay at 620 nm. Results: All strains showed sensitivity to honey with MIC equal to 25% (vol/vol). The MIC (%) values of honey for all studied S. aureus (MRSA and MSSA) isolates ranged between 18-100% (v/v). Conclusion: Honey with confirmed, antibacterial activity has the potential to be an efficient treatment complementary for diabetic foot ulcers infected or at risk of infection with S. aureus.

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Section: Discussionmentioning

confidence: 98%

Antibacterial Activity of Honey against Methicillin-Resistant and Sensitive Staphylococcus Aureus Isolated from Patients with Diabetic Foot Ulcer

Mirzaei¹,

Karamolah²,

Mahnaie³

et al. 2020

TOMICROJ

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“…The high osmolarity, flavonoids, phytochemical constituents (methyl glyoxal which is 1,2 dicarbonyl compound), lysine/ arginine side chains are involved in the uptake of these constituents in certain diseases. These components of manuka honey and its importance in combating the antimicrobial resistance of P. aeruginosa have been described by Shenoy et al and Alvarez-Suarez et al (Shenoy et al 2012 ; Alvarez-Suarez et al 2014 ).…”

Section: Antimicrobial Peptides (Amps)mentioning

confidence: 89%

Antimicrobial peptide polymers: no escape to ESKAPE pathogens—a review

Mukhopadhyay

Prasad

Mehta

et al. 2020

World J Microbiol Biotechnol

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Antimicrobial resistance (AMR) is one of the significant clinical challenges and also an emerging area of concern arising from nosocomial infections of ESKAPE pathogens, which has been on the rise in both the developed and developing countries alike. These pathogens/superbugs can undergo rapid mutagenesis, which helps them to generate resistance against antimicrobials in addition to the patient's non-adherence to the antibiotic regimen. Sticking to the idea of a 'one-size-fits-all' approach has led to the inappropriate administration of antibiotics resulting in augmentation of antimicrobial resistance. Antimicrobial peptides (AMPs) are the natural host defense peptides that have gained attention in the field of AMR, and recently, synthetic AMPs are well studied to overcome the drawbacks of natural counterparts. This review deals with the novel techniques utilizing the bacteriolytic activity of natural AMPs. The effective localization of these peptides onto the negatively charged bacterial surface by using nanocarriers and structurally nanoengineered antimicrobial peptide polymers (SNAPPs) owing to its smaller size and better antimicrobial activity is also described here.

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“…In a study published by the Journal of Global Infectious Diseases, Pseudomonas was also found in the honey samples [21]. That experiment examined the antimicrobial properties of honey and its ability to kill P. aeruginosa [21].…”

Section: Discussionmentioning

confidence: 99%

The microbes found in the honey of New York City beehives

Weiss

Mayle

Nash

2020

Preprint

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Bees are incredibly important to the Earth's ecosystem and provide humans with a variety of fruits and vegetables; however, due to Colony Collapse Disorder, hives are dying at an alarming rate. Colony Collapse Disorder is caused by a number of factors such as pesticides and bacteria that kill the bees. With the increase of urban beekeeping created in an effort to replenish the bee population, little is known about the microbes the bees are interacting with in New York City. This research looked at what microbes the bees came in contact with to use as a resource in identifying the differences between the neighborhoods. Two methods were used to extract the DNA, one looking at gram-positive and gram-negative bacteria and the other looking at only gram-positive. The samples were taken from around New York City, Westchester County and Pennsylvania. The Pennsylvania sample was collected from a container of honey bought from Trader Joe's. The reason both urban and rural samples were used was to see if there is an obvious difference in the microbes found between them.

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Honey as an antimicrobial agent against Pseudomonas aeruginosa isolated from infected wounds

Cited by 30 publications

References 28 publications

Antibacterial Activity of Honey against Methicillin-Resistant and Sensitive Staphylococcus Aureus Isolated from Patients with Diabetic Foot Ulcer

Antibacterial Activity of Honey against Methicillin-Resistant and Sensitive Staphylococcus Aureus Isolated from Patients with Diabetic Foot Ulcer

Antimicrobial peptide polymers: no escape to ESKAPE pathogens—a review

The microbes found in the honey of New York City beehives

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