1988
DOI: 10.1111/j.1365-2273.1988.tb00757.x
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Homograft materials in otolaryngology: the risk of transmitting human immunodeficiency virus

Abstract: Homograft materials are extensively used in various surgical procedures in otolaryngology, but with the increasing prevalence of human immunodeficiency virus (HIV) in the population this practice must be reviewed. Careful donor selection and antibody testing reduce but do not fully eliminate the risk of an HIV positive donor, and current preservation techniques may not inactivate all viruses. The use of homograft tissues should therefore be reconsidered as autograft or prosthetic material provides a satisfacto… Show more

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Cited by 8 publications
(5 citation statements)
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“…In the past, lyophilized human dura or substitute materials from animal origin like bovine pericardium or dura mater were used. These materials are no longer available due to reports of transmission of prion diseases such as Creutzfeld-Jakob disease or HIV, respectively [23][24][25].…”
Section: Introductionmentioning
confidence: 99%
“…In the past, lyophilized human dura or substitute materials from animal origin like bovine pericardium or dura mater were used. These materials are no longer available due to reports of transmission of prion diseases such as Creutzfeld-Jakob disease or HIV, respectively [23][24][25].…”
Section: Introductionmentioning
confidence: 99%
“…10,11 The possibility of transmitting certain diseases (AIDS, Creutzfeldt-Jakob disease) by using homografts is now widely accepted. 12,13 Thus, there is renewed interest in prostheses made from biologically com-patible materials (Polycel, Proplast and Plastipore), bioceramics (aluminium hydroxide, ceravital, hydroxylapatite) and, very recently, ionomeric cement, gold and titanium.…”
Section: Introductionmentioning
confidence: 99%
“…Attention has rightly focused on transmission of the causative agent to recipients of human donor material. Fear of transmission of HIV has led to considerable re-evaluation of the role of homograft materials in middle ear surgery (Davis, 1988). It is recognized practice to perform the first steps of surgical approach to the mastoid antrum without the use of an operating microscope (Ransome, 1986).…”
Section: Introductionmentioning
confidence: 99%