Homograft materials in otolaryngology: the risk of transmitting human immunodeficiency virus

Davis, Anne E.

doi:10.1111/j.1365-2273.1988.tb00757.x

Cited by 8 publications

(5 citation statements)

References 7 publications

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“…In the past, lyophilized human dura or substitute materials from animal origin like bovine pericardium or dura mater were used. These materials are no longer available due to reports of transmission of prion diseases such as Creutzfeld-Jakob disease or HIV, respectively [23][24][25].…”

Section: Introductionmentioning

confidence: 99%

In vitro and in vivo studies on blends of isotactic and atactic poly (3-hydroxybutyrate) for development of a dura substitute material

et al. 2006

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Section: Introductionmentioning

confidence: 99%

In vitro and in vivo studies on blends of isotactic and atactic poly (3-hydroxybutyrate) for development of a dura substitute material

et al. 2006

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“…10,11 The possibility of transmitting certain diseases (AIDS, Creutzfeldt-Jakob disease) by using homografts is now widely accepted. 12,13 Thus, there is renewed interest in prostheses made from biologically com-patible materials (Polycel, Proplast and Plastipore), bioceramics (aluminium hydroxide, ceravital, hydroxylapatite) and, very recently, ionomeric cement, gold and titanium.…”

Section: Introductionmentioning

confidence: 99%

Effect of KTP laser on implants used in middle-ear surgery

et al. 2002

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The present study is intended to explore the effects of the KTP laser on various types of implant, used in middle-ear surgery. A laboratory study was undertaken to evaluate the interaction between the KTP laser (KTP-532 Orion Laser, Laserscope, UK) and individual middle-ear implants. A variety of middle-ear implants were used: a silicone sheet, Teflon, hydroxylapatite, ionomeric cement, gold and titanium prostheses as well as gelfoam. Following exposure to the laser, these implants were studied by direct inspection using an operating microscope. The KTP laser induced no detectable alteration in any of the implants when they were clean and dry. However, in the presence of fresh blood, under the influence of the energy of the absorbed laser, the silicone burnt and melted and the Teflon piston was vaporized. Likewise, a few tiny holes appeared on the surface of the ionomeric implant and then the prosthesis deformed. The hydroxylapatite implant broke into two pieces. However, no detectable alteration could be observed on gold or titanium pistons, even in the presence of blood. The authors conclude, that in the presence of blood, interaction between the KTP laser and both silicone and hydroxylapatite implants needs to be avoided. Teflon prostheses can be cautiously vaporized. Gold and titanium prostheses were unaffected by laser even in the presence of blood.

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“…Attention has rightly focused on transmission of the causative agent to recipients of human donor material. Fear of transmission of HIV has led to considerable re-evaluation of the role of homograft materials in middle ear surgery (Davis, 1988). It is recognized practice to perform the first steps of surgical approach to the mastoid antrum without the use of an operating microscope (Ransome, 1986).…”

Section: Introductionmentioning

confidence: 99%