Homogeneous voltammetric sensing strategy for lead ions based on aptamer gated methylthionine chloride@UiO-66-NH₂ framework as smart target-stimulated responsive nanomaterial

Abstract

Herein an innovative electrochemical method is proposed for the determination of lead ion (Pb2+) based on a homogeneous voltammetric (HVC) sensing strategy via preparing aptamer gated methylthionine chloride@UiO-66-NH2 framework as...

High Peroxidase-Mimicking Metal–Organic Frameworks Decorated with Platinum Nanozymes for the Colorimetric Detection of Acetylcholine Chloride and Organophosphorus Pesticides via Enzyme Cascade Reaction

“…As coordination polymers featuring a porous-network nanostructure, metal–organic framework (MOF) materials offer well-defined pore nanostructures, high surface areas, large porosities, and structural diversity and are considered as desirable potential nanozymes to imitate the catalytic activity of natural enzymes. − In the last few decades, there have been various works devoted to the design, synthesis, and application of new MOF structures . Wang, Serre, and co-workers prepared MIP-201 MOF, which exhibits superior selectivity and catalytic activity and high tolerance toward the reaction conditions in a wide range of pH values; Zhong et al constructed a simulated multienzyme tandem catalytic system by combining glucose oxidase with MOF-545­(Fe), where MOF-545­(Fe) not only serves as a carrier for immobilizing enzymes but also has the catalytic activity to cooperate with natural enzymes for the cascade reactions; Luo et al introduced Mn ions into Fe-MOF for the improvement of the oxidase-like activity through the synergistic enhancement of the electron transfer rate by Mn and Fe elements; meanwhile, Ruan et al synthesized a graphene oxide/Fe-MOF nanozyme nest and exploited its application for the detection of benzo­[ a ]­pyrene.…”

Target-Controlled Redox Reaction and Ru(II) Release of a Smart Metal–Organic Framework Nanomaterial for Highly Sensitive Ratiometric Homogeneous Electroanalysis of Cadmium(II)

“…In recent years, the electrochemical technology has aroused intense attention in the detection of Cd 2+ , which is characterized by high sensitivity, fast response, and low cost. − As for the developed electrochemical sensing method for Cd 2+ , there are generally two common patterns. , One is the traditional nanomaterial-based anodic stripping voltammetry technology (ASV), which involves two steps: electrodeposition and reoxidation. ,− For instance, Sun et al prepared a graphdiyne/graphene nanohybrid-modified electrode to achieve the ASV detection of Cd 2+ upon the electrodeposition of 300 s at 1.2 V, which enables Cd 2+ to be reduced to Cd 0 ; similarly, Guo and his colleagues prepared a Co-TIC4R-I electrode to achieve sensitive ASV detection of Cd 2+ after 300 s electrodeposition at −1.0 V. The other pattern is the biosensors by using various biorecognition elements and introducing electroactive probes (e.g., ferrocene and thionine). , For instance, Yuan’s group assembled a Pd@Cu@Pt/DNA-ferrocene-modified electrode for the electrochemical detection of Hg 2+ ; herein, the ferrocene molecule was adopted as an electroactive probe. There is no doubt that these electrochemical methods can achieve sensitive detection for Cd 2+ ; however, suitable electrode modification processes and modifiers are generally inevitable for these methods, which are relatively complex and easily pose negative effects on the sensing activity of materials, disturbing the sensitivity, stability, and reproducibility of the sensing assay; in addition, modifiers may fall off from the electrode surface easily.…”

Review—Recent Advances in Electrochemical Sensing of Lead Ion

“…Lead is considered one of the most toxic elements due to its environmental and human health hazards, and it poses a severe threat to human health through the air, drinking water, and food. 1,2 For example, when lead and its compounds enter the body, it will cause harm to multiple systems such as nerves, hematopoiesis, digestion, kidneys, cardiovascular and endocrine systems. [3][4][5] People experience symptoms such as dizziness, fatigue, insomnia, anemia, and low immunity.…”