Homocysteine May Decrease Glucose Uptake and Alter the Akt/GSK3β/GLUT1 Signaling Pathway in Hippocampal Slices: Neuroprotective Effects of Rivastigmine and Ibuprofen

Novel ibuprofen prodrug: A possible promising agent for the management of complications of Alzheimer’s disease

“…Studies conducted in the past reported that ibuprofen could modulate inflammatory process as well reduce the production of proinflammatory cytokines ( Albertini et al, 2021 ). Studies also indicated that ibuprofen administration protects neurons against glutamate toxicity ( Ramires Junior et al, 2023 ). Besides, ibuprofen was found to suppress the neuritic plaque formation when administered in AD ( Litus et al, 2022 ).…”