Homocysteine and methylmalonic acid in Phenylketonuria patients
Giovana Regina Weber Hoss,
Fernanda Sperb-Ludwig,
Tássia Tonon
et al.
Abstract:Hyperhomocysteinemia and vitamin B12 deficiency have been reported in patients
with phenylketonuria. In this study, total homocysteine (tHcy) and methylmalonic
acid (MMA) levels were analyzed in samples from 25 phenylketonuria (PKU)
patients. Comparisons were made between pre- and post-treatment values (n= 3);
on treatment values, between periods with high and normal/low phenylalanine
(Phe) levels (n= 20); and in women before, during and after pregnancy (n= 3).
THcy levels decreased after treating PKU with met… Show more
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