“… 7 When the level of Hcy increases abnormally, it leads to hyperhomocysteinemia (HHcy). HHcy has been indicated as a risk factor for a variety of disorders, such as cardiovascular diseases, 8 , 9 , 10 neural tube defects, 11 , 12 atrial fibrillation, 13 , 14 Alzheimer's disease, 15 , 16 cancer, 17 , 18 multiple sclerosis, 19 , 20 , 21 migraine, 22 , 23 and other diseases. Additionally, recent evidence showed that HHcy contributed to the development of PD.…”