Homochiral metal–organic frameworks as heterogeneous catalysts

Abstract

Homochiral metal–organic frameworks (HMOFs) are attractive materials for asymmetric catalysis because they possess high surface area and uniform active sites.

Synthesis of Chiral MOF‐74 Frameworks by Post‐Synthetic Modification by Using an Amino Acid

“…In this context,c hiral metal-organic frameworks( MOFs) [16] have emerged as an ew class of potential asymmetricheterogeneous catalyst. [17][18][19][20] As traightforward approacht owardst he synthesis of chiral MOFsr elies on the appropriate combination of metal ions and enantiopure organic linkers. [18,[21][22][23][24][25] Although some efficient catalysts are designed by using this approach,t he synthesis of the chiral linkers often entails lengthy multi-step procedures.…”

“…[17][18][19][20] As traightforward approacht owardst he synthesis of chiral MOFsr elies on the appropriate combination of metal ions and enantiopure organic linkers. [18,[21][22][23][24][25] Although some efficient catalysts are designed by using this approach,t he synthesis of the chiral linkers often entails lengthy multi-step procedures. An alternativem ethodology focuses on the post-synthetic modification of achiral MOFs by either covalent binding of chiralg roups on the organic linkers [26] or by coordinating them to the metal ions.…”

“…Alternatively, the use of heterogeneous catalytic systems enables the easy recovery of the catalyst from the reaction medium and its reuse in consecutive cycles, therefore resulting in low‐cost applications. In this context, chiral metal–organic frameworks (MOFs) [16] have emerged as a new class of potential asymmetric heterogeneous catalyst [17–20] …”

“…A straightforward approach towards the synthesis of chiral MOFs relies on the appropriate combination of metal ions and enantiopure organic linkers [18, 21–25] . Although some efficient catalysts are designed by using this approach, the synthesis of the chiral linkers often entails lengthy multi‐step procedures.…”

Copper-catalyzed one-pot domino reactions via C–H bond activation: synthesis of 3-aroylquinolines from 2-aminobenzylalcohols and propiophenones under metal–organic framework catalysis

“…[25][26][27] In the porous framework, both organic linkers and metal clusters could be useful for catalysis, facilitating the interaction between active sites and reactants. 22,[28][29][30] Although long lists of MOFs have been published with detailed data on syntheses and characterizations, more efforts should be devoted to their applications in catalysis. [31][32][33][34] During the past decade, a long series of organic reactions have been conducted utilizing MOFs as catalysts with fascinating results being reported.…”