Homeopathy, sensation of well-being and CD4 levels: a placebo-controlled, randomized trial

Kuzeff, R.M.

doi:10.1016/s0965-2299(98)80050-2

Cited by 13 publications

(5 citation statements)

References 2 publications

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“…In this field, there is a body of pre-clinical research suggesting that homeopathic remedies may regulate the immune system at cellular and/or systemic levels ( 28 – 30 ). There are also preliminary ex vivo observations of significant changes of immune cells (CD4 lymphocytes) in people treated with high potencies of homeopathic medicines ( 31 ) and, broadly speaking, it has been suggested that T cells can be the target of immunoregulation by a range of complementary and alternative medicines ( 32 ).…”

Section: Introductionmentioning

confidence: 99%

Immunology and Homeopathy. 4. Clinical Studies—Part 1

Bellavite

Ortolani

Pontarollo

et al. 2006

Evidence-Based Complementary and Alternative Medicine

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The evidence-based research of the effectiveness of homeopathic medicines in common immunologic disorders is reviewed. In part 1, we introduce methodological issues of clinical research in homeopathy, and criteria utilized to evaluate the literature. Then 24 studies (12 randomized and 12 non-randomized) on common upper respiratory tract infections and otorhinolaryngologic complaints are described. In part 2, the focus will be on allergic diseases and the effectiveness of homeopathy will be globally evaluated and discussed using the criteria of evidence-based medicine.

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Section: Introductionmentioning

confidence: 99%

Immunology and Homeopathy. 4. Clinical Studies—Part 1

Bellavite

Ortolani

Pontarollo

et al. 2006

Evidence-Based Complementary and Alternative Medicine

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“…One wonders if clinical studies using 10 or fewer remedies in a sample population of 60 patients have been adequately individualized [48,49]. One study used 29 different remedies for 36 patients [14]. One could counter that the latter study included patients with multiple diagnoses, whereas the other studies focussed on migraines [48] and warts [49].…”

Section: Discussionmentioning

confidence: 99%

“…He was thereby sufficiently inspired to give homeopathy one last go in his practice, in the form of a prospective double-blind randomized placebo-controlled study [14]. The author was further inspired by the fact that if a study is prospective, double-blind, randomized and placebo controlled, then it is scientifically and mathematically prudent to accept that the observed difference is valid.…”

Section: Introductionmentioning

confidence: 99%

A review of use of enantiomers in homeopathy

Kuzeff

2014

Homeopathy

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This paper reviews publications of laboratory experiments using pairs of enantiomers in homeopathy. Many molecules in nature have geometry which enables them to exist as nonsuperimposable mirror images or enantiomers. Modulation of toxicity of such molecules provides possibility for therapeutics, since they target multiple points in biochemical pathways. It was hypothesized that toxicity of a chemical agent could be counteracted by a homeopathic preparation of the enantiomer of the chemical agent (patents applied for: PCT/AU2003/000219-PCT/AU2008/001611). A diverse body of data, including controlled laboratory studies, supports the conclusion that toxicity of optical isomers may be inhibited by homeopathic enantiomer preparations. These data were obtained with minimal or no pretesting to determine optimal test solutions. Inhibition of the excitotoxic neurotransmitter Lglutamic acid with homeopathic preparations of D-glutamic acid indicates the latter may be of use for amelioration of symptoms of disturbances of mood. Similarly, homeopathic preparation of (+)-nicotine may be of use for inhibition of effects of nicotine in tobacco.

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“…The study also suggests that homoeopathic medicines may affect CD4 levels. 18 The study design of these clinical trials might be a ray of hope in exploring the immunomodulatory or antiviral effects of the above-mentioned homoeopathic medicines.…”

Section: Clinical Trial Evidence For Effects Of Homoeopathic Medicine...mentioning

confidence: 99%

Researcher's Perspective on Upper Respiratory Tract Infections, Immunomodulatory and Antiviral Effects of High-Dilution Medicines

Patil

2023

Homœopathic Links

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Homoeopathic system of medicine is based on Law of Similars, that is, principle of ‘Like cures like’. These ultra-diluted forms of medicine are prescribed on the basis of symptom similarity (individualised therapeutic) which helps in stimulating body's own defence mechanisms to fight against the pathogen. Homoeopathy had been tested in various preclinical studies for deciphering its properties of immunomodulatory on markers like tumour necrosis factor alpha, CD4 and antiviral effects in adenovirus 5, herpes simplex virus-1, respiratory syncytial virus and human rhinovirus which are elaborated. Effects of homoeopathic medicine on mild viral infections and CD4+ count are elaborated. A note on study design based on clinical trial of upper respiratory tract infections might be helpful in designing study for exploring immunomodulatory and antiviral effects of homoeopathic medicines.

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Homeopathy, sensation of well-being and CD4 levels: a placebo-controlled, randomized trial

Cited by 13 publications

References 2 publications

Immunology and Homeopathy. 4. Clinical Studies—Part 1

Immunology and Homeopathy. 4. Clinical Studies—Part 1

A review of use of enantiomers in homeopathy

Researcher's Perspective on Upper Respiratory Tract Infections, Immunomodulatory and Antiviral Effects of High-Dilution Medicines

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