HOMEFOOD randomised trial – Six-month nutrition therapy improves quality of life, self-rated health, cognitive function, and depression in older adults after hospital discharge

Blondal, B.S.; Geirsdóttir, Ólöf Guðný; Halldórsson, Thorhallur I.; Beck, Anne Marie; Jónsson, Pálmi V.; Ramel, Alfons

doi:10.1016/j.clnesp.2022.01.010

Cited by 8 publications

(6 citation statements)

References 53 publications

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“…The final study reviewed in this section was led by Tanaka et al, entitled “Metabolomic profile of different dietary patterns and their association with frailty index in community‐dwelling older men and women.” The authors analyzed whether adherence to healthy dietary patterns, such as the Mediterranean diet (MD), Mediterranean–Dietary Approaches to Stop Hypertension Diet Intervention for Neurodegenerative Delay (MIND), and Alternate Healthy Eating Index 2010 (AHEI), is associated with with frailty through metabolomic biomarkers of dietary patterns and mediation analysis 43 . The population was 806 participants of the Baltimore Longitudinal Study of Aging.…”

Section: Resultsmentioning

confidence: 99%

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Highlights in the clinical nutrition literature: A critical appraisal of current research

Stoppe,

Elke,

Silvstre

et al. 2024

J Parenter Enteral Nutr

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Within the American Society for Parenteral and Enteral Nutrition (ASPEN), the Physician Engagement Committee (PEC) was created in 2017 by the ASPEN Board of Directors with the goal of growing the physician community both nationally and internationally. The PEC meets each month throughout the year to develop educational and research initiatives. In 2022, the PEC began an initiative to systematically review and evaluate practice‐changing literature annually with the overall aim to highlight these studies at the annual ASPEN conferences and to critically discuss the potential clinical implications. The objective of the held meeting session was to present identified key papers in the fields of critical care medicine, gastroenterology and hepatology, and adult internal medicine that were published in 2022, which would complement the knowledge of the pathogenesis, diagnosis, and management of nutrition topics as well as to identify areas of future research. Overall, several large‐scale randomized controlled studies were identified in each of these sections, with practice‐changing major results. This manuscript summarizes the information that was presented and the discussions that followed.

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Section: Resultsmentioning

confidence: 99%

“…The final study reviewed in this section was led by Tanaka et al 2010 (AHEI), is associated with with frailty through metabolomic biomarkers of dietary patterns and mediation analysis. 43 The population was 806 participants of the Baltimore Longitudinal Study of Aging.…”

Section: Year In Review: Adult Internal Medicinementioning

confidence: 99%

Highlights in the clinical nutrition literature: A critical appraisal of current research

Stoppe,

Elke,

Silvstre

et al. 2024

J Parenter Enteral Nutr

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“…A key strength is the inclusion of a validated neurocognitive test battery in the current study allowing a comprehensive assessment of performance in both memory and non-memory domains of cognition as used in other multidomain interventions in adults at increased dementia risk 42. Prior studies in undernourished patients have relied on the limited MMSE global cognition to measure cognitive performance 25. While MMSE is a validated screener for cognitive impairment, it provides limited examination of visuospatial cognitive ability, long-term memory and language functions.…”

Section: Discussionmentioning

confidence: 99%

“…To date, most studies have focused on the impact of diet on physical function,22 with limited number of interventions targeting undernutrition for cognitive benefit. Short-term treatment of undernutrition has been shown to improve both nutritional status and cognitive performance 23–25. However, small sample sizes as well as differences in residential status of study populations and nutritional interventions (dietetic counselling,23 oral supplementation,24 25 meal provision25), and cognitive outcomes make it difficult to know whether addressing undernutrition could protect against cognitive decline.…”

Section: Introductionmentioning

confidence: 99%

“…Short-term treatment of undernutrition has been shown to improve both nutritional status and cognitive performance 23–25. However, small sample sizes as well as differences in residential status of study populations and nutritional interventions (dietetic counselling,23 oral supplementation,24 25 meal provision25), and cognitive outcomes make it difficult to know whether addressing undernutrition could protect against cognitive decline. Hence, trials are warranted to test the efficacy of intervention for undernutrition in populations at increased risk of cognitive decline but not yet cognitively impaired and may benefit from early intervention.…”

Section: Introductionmentioning

confidence: 99%

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Effects of PROtein enriched MEDiterranean Diet and EXercise on nutritional status and cognition in adults at risk of undernutrition and cognitive decline: the PROMED-EX Randomised Controlled Trial.

Ward,

Reid-McCann,

Brennan

et al. 2023

BMJ Open

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IntroductionUndernutrition leading to unplanned weight loss is common in older age and has been linked to increased dementia risk in later life. Weight loss can precede dementia by a decade or more, providing a unique opportunity for early intervention to correct undernutrition and potentially prevent or delay cognitive impairment. The combined effects of diet and exercise on undernutrition have not yet been evaluated. The objective of this trial is to determine the effect of a protein-enriched Mediterranean diet, with and without exercise, on nutritional status and cognitive performance in older adults at risk of undernutrition and cognitive decline.MethodsOne hundred and five participants aged 60 years and over at risk of undernutrition and with subjective cognitive decline will be recruited to participate in a 6-month, single-blind, parallel-group randomised controlled trial. Participants will be block randomised into one of three groups: group 1—PROMED-EX (diet+exercise), group 2—PROMED (diet only) and group 3—standard care (control). The primary outcome is nutritional status measured using the Mini Nutritional Assessment. Secondary outcomes include cognitive function, nutritional intake, body composition, physical function and quality of life. Mechanistic pathways for potential diet and exercise-induced change in nutritional status and cognition will be explored by measuring inflammatory, metabolic, nutritional and metabolomic biomarkers.Ethics and disseminationThe study is approved by the UK Office for Research Ethics Committee (ref: 21/NW/0215). Written informed consent will be obtained from participants prior to recruitment. Research results will be disseminated to the public via meetings and media and the scientific community through conference presentations and publication in academic journals.Trial registration numberClinicalTrials.gov Registry (NCT05166564).

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Nutrition and Hydration

Roigk,

Graeb,

Geirsdóttir

et al. 2023

Perspectives in Nursing Management and Care for Older Adults

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Nutrition and hydration are fundamental aspects of healthcare, especially in the care of older people, particularly those in hospitals or in long-term care facilities. Worldwide, nurses are ‘best-placed’ coordinators of interdisciplinary nutritional management and care processes. Even so, it is essential that nurses collaborate with other healthcare specialists as an interdisciplinary team to provide high-quality care that reflects patients’ needs for assessment, intervention, and health promotion. When an interdisciplinary team work collaboratively, care is more successful, improves patient outcomes, and reduces the risk of in-hospital and long-term mortality.The care process begins with screening and monitoring of the nutritional status and fluid intake of all older people within 24 h of admission. In the case of positive screening, comprehensive assessment and involvement of other team members should undertake to understand the underlying problem. Appropriate food and appealing meals, snacks, and drinks should be available and offered with recommended amounts of energy, protein, vitamins, minerals (particularly calcium), and water. This should be complemented with supplementary drinks if intake is not adequate. The prescription of vitamin D and calcium should be discussed.Patient-centred and evidence-based information should provide and interventions in the case of end-of-life care should be appropriate discussed. Educating, informing, and involving patients and families increases their level of health literacy. Malnutrition and/or dehydration management should be included in the discharge plan.The aim of this chapter is to increase awareness of nurses’ responsibility, within a multidisciplinary team, for assessment and intervention of nutrition and hydration, examine the issues pertaining to nutrition and fluid balance in older people and outline the nature, assessment and interventions relating to malnutrition and dehydration.

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HOMEFOOD randomised trial – Six-month nutrition therapy improves quality of life, self-rated health, cognitive function, and depression in older adults after hospital discharge

Cited by 8 publications

References 53 publications

Highlights in the clinical nutrition literature: A critical appraisal of current research

Highlights in the clinical nutrition literature: A critical appraisal of current research

Effects of PROtein enriched MEDiterranean Diet and EXercise on nutritional status and cognition in adults at risk of undernutrition and cognitive decline: the PROMED-EX Randomised Controlled Trial.

Nutrition and Hydration

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