Home Use of Automated External Defibrillators for Sudden Cardiac Arrest

Bardy, Gust H.; Lee, Kerry L.; Mark, Daniel B.; Poole, Jeanne E.; Toff, William D.; Tonkin, Andrew; Smith, Warren; Dorian, Paul; Packer, Douglas L.; White, Roger D.; Longstreth, W. T.; Anderson, Jill; Johnson, George; Bischoff, Eric D.; Yallop, Julie Jane; McNulty, Steven E.; Ray, Linda Davidson; Clapp‐Channing, Nancy E.; Rosenberg, Yves; Schron, Eleanor B.

doi:10.1056/nejmoa0801651

Cited by 268 publications

(156 citation statements)

References 27 publications

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“…Among the latter group there are many who may have never had symptoms suggestive of heart disease or were not evaluated for other reasons, such as disparate access to health care. Recent observations such as the recently reported Home Automated External Defibrillation trial (37) have confirmed the present, remarkably low annual mortality rate (2%) among patients with treated acute anterior myocardial infarction who did not meet criteria for an implantable defibrillator. This reduction in mortality may in fact have been the single most important reason that home use of the automated external defibrillator did not benefit this group of patients.…”

Section: Findings From Population-based Studiessupporting

confidence: 76%

Epidemiology of Sudden Cardiac Death: Clinical and Research Implications

Chugh

Reinier

Teodorescu

et al. 2008

Progress in Cardiovascular Diseases

595

458

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The current annual incidence of sudden cardiac death in the US is likely to be in the range of 180-250,000 per year. Coinciding with the decreased mortality from coronary artery disease, there is evidence pointing toward a significant decrease in rates of sudden cardiac death in the US during the second half of the twentieth century. However the alarming rise in prevalence of obesity and diabetes in the first decade of the new millennium both in the US and worldwide, would indicate that this favorable trend is unlikely to persist. We are likely to witness a resurgence of coronary artery disease and heart failure, as a result of which sudden cardiac death will have to be confronted as a shared and indiscriminate, worldwide public health problem. There is also increasing recognition of the fact that discovery of meaningful and relevant risk stratification and prevention methodologies will require careful prospective community-wide analyses, with access to large archives of DNA, serum and tissue that link with well-phenotyped databases. The purpose of this review is to summarize current knowledge of sudden cardiac death epidemiology. We will discuss the significance and strengths of community-wide evaluations of sudden cardiac death, summarize recent observations from such studies, and finally highlight specific potential predictors that warrant further evaluation as determinants of sudden cardiac death in the general population.

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Section: Findings From Population-based Studiessupporting

confidence: 76%

Epidemiology of Sudden Cardiac Death: Clinical and Research Implications

Chugh

Reinier

Teodorescu

et al. 2008

Progress in Cardiovascular Diseases

595

458

View full text Add to dashboard Cite

show abstract

“…A randomized, clinical trial of AED use in the home after AMI failed to identify a survival benefit. 34 In the relatively small but important minority of patients in whom an increased risk of cardiac arrest is predictable on the basis of clinical risk factors, implantation of a prophylactic defibrillator offers distinct advantages. An ICD, which continuously monitors a patient's rhythm, affords the benefit of minimal delay between the onset of a potentially fatal tachyarrhythmia and its automatically instituted treatment.…”

Section: Defibrillator Technologies and Limitationsmentioning

confidence: 99%

Wearable Cardioverter-Defibrillator Therapy for the Prevention of Sudden Cardiac Death

Piccini¹,

Allen²,

Kudenchuk³

et al. 2016

Circulation

117

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“…18 Patients were randomized at 178 centers in 7 countries to the usual strategy of calling EMS and performing CPR, or using an AED followed by calling EMS and performing CPR. The median patient age was 62 years and 17.4% were female.…”

Section: Home Use Of Aeds To Prevent Sudden Death In Individual High-mentioning

confidence: 99%

The Effectiveness and Cost Effectiveness of Public‐Access Defibrillation

Winkle

2010

Clinical Cardiology

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Many sudden cardiac deaths are due to ventricular fibrillation (VF). The use of defibrillators in hospitals or by outpatient emergency medical services (EMS) personnel can save many cardiac‐arrest victims. Automated external defibrillators (AEDs) permit defibrillation by trained first responders and laypersons. AEDs are available at most public venues, and vast sums of money are spent installing and maintaining these devices. AEDs have been evaluated in a variety of public and private settings. AEDs accurately identify malignant ventricular tachyarrhythmias and frequently result in successful defibrillation. Prompt application of an AED shows a greater number of patients in VF compared with initial rhythms documented by later‐arriving EMS personnel. Survival is greatest when the AED is placed within 3 to 5 minutes of a witnessed collapse. Community‐based studies show increased cardiac‐arrest survival when first responders are equipped with AEDs rather than waiting for paramedics to defibrillate. Wide dissemination of AEDs throughout a community increases survival from cardiac arrest when the AED is used; however, the AEDs are utilized in a very small percentage of all out‐of‐hospital cardiac arrests. AEDs save very few lives in residential units such as private homes or apartment complexes. AEDs are cost effective at sites where there is a high density of both potential victims and resuscitators. Placement at golf courses, health clubs, and similar venues is not cost effective; however, the visible devices are good for public awareness of the problem of sudden cardiac death and provide reassurance to patrons. Copyright © 2010 Wiley Periodicals, Inc.

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Home Use of Automated External Defibrillators for Sudden Cardiac Arrest

Cited by 268 publications

References 27 publications

Epidemiology of Sudden Cardiac Death: Clinical and Research Implications

Epidemiology of Sudden Cardiac Death: Clinical and Research Implications

Wearable Cardioverter-Defibrillator Therapy for the Prevention of Sudden Cardiac Death

The Effectiveness and Cost Effectiveness of Public‐Access Defibrillation

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