Abstract:SummaryFifty-four patients were studied prospectively to evaluate home-readiness after a small dose (1 or 2 ml) of subarachnoid hyperbaric 0.5% bupivacaine. The block regressed significantly earlier in the 1 ml group than in the 2 ml group (p < 0.05). The patients were also able to walk significantly earlier in the 1 ml group (median 161 min and 231 min in the 1 ml and 2 ml groups, respectively) (p < 0.05). However, there were no significant differences between the groups in time of ability to void. We conclud… Show more
“…The mean time to first passing urine was longer than the mean time to the complete resolution of the motor and sensory block. This is in accordance with the studies of Ben-David et al [19] and Tarkkila et al [21] whose subjects were able to walk before they could micturate. Our patients were advised not to attempt to pass urine before they had a natural urge to do so.…”
supporting
confidence: 93%
“…The total motor block score (modified Bromage scale; mean Ϯ SD) on the operated and nonoperated sides in patients receiving near isobaric (group 1; n ¼ 30) and hypobaric (group 2; n ¼ 30) bupivacaine (6 mg) for spinal anaesthesia. reported after hyperbaric bupivacaine spinal anaesthesia [5,21]. In our present study, there was no evidence of transient neurological sequelae.…”
supporting
confidence: 50%
“…Although spinal anaesthesia can be achieved with hypo-and hyperbaric solutions of bupivacaine [10,[18][19][20][21], transient neurological symptoms have been Anaesthesia, 1999, 54, pages 540-545 K. S. Kuusniem et al…”
SummaryThe results of studies on the effect of volume, concentration or total dose of local anaesthetic on the spread of spinal anaesthesia are inconclusive. Most support the assumption that the total dosage is more important than the volume. We compared low-dose bupivacaine (6 mg) in 0.5% and 0.18% solutions as sole anaesthetic to achieve predominantly unilateral spinal anaesthesia for knee arthroscopy. Sixty patients were randomly allocated to two groups to receive either 1.2 ml 0.5% bupivacaine (6 mg) (n ¼ 30) or 3.4 ml 0.18% hypobaric bupivacaine (6.1 mg) (n ¼ 30). Drugs were administered at the L 3-4 interspace with the patient in the lateral position. Patients remained in this position for 20 min before being turned supine for the operation. Spinal block was assessed by pinprick and modified Bromage scale and compared between the operated and nonoperated sides. No significant changes were found in the spread or duration of sensory or motor block (p > 0.05). The haemodynamic changes were also similar between the groups. The same pinprick level of analgesia, degree of motor block and duration of spinal anaesthesia was obtained with bupivacaine (6 mg) in low (1.2 ml) or high (3.4 ml) volumes. The ideal spinal anaesthesia for ambulatory surgery should provide good surgical anaesthesia with rapid recovery from sensory and motor block [1]. Lignocaine has been widely advocated for ambulatory anaesthesia but there are concerns about possible neurotoxicity. Recent editorials have questioned the use of hyperbaric 5% lignocaine for spinal anaesthesia [2][3][4]. In contrast, the frequency of radiating backache after bupivacaine has been reported as less than 1% [5,6]. There is increasing interest in the use of small doses of bupivacaine for spinal anaesthesia.There has been controversy concerning the relationship between volume, concentration and total dose of spinally administered drugs. Most of the studies suggest that the total dosage is more important than the volume [7][8][9]. In these studies, the doses of bupivacaine were fairly large. Sheskey et al. used 10, 15 and 20 mg doses [7] and Bengtsson et al. used bupivacaine 22.5 mg [8]. In the study of Cherng et al., plain bupivacaine 15 mg was diluted with cerebrospinal fluid (CSF) [9]. The effect of volume on spinal anaesthesia when a small dose (5-10 mg) of hypobaric bupivacaine is used has not been investigated.In a previous study, we achieved predominantly unilateral spinal anaesthesia with minimal sensory and motor block on the nonoperated side using a low dose of hypobaric 0.18% bupivacaine [10]. We have now compared low-dose bupivacaine (6 mg) in two volumes for predominantly unilateral spinal anaesthesia for day-case knee arthroscopy.
Methods
“…The mean time to first passing urine was longer than the mean time to the complete resolution of the motor and sensory block. This is in accordance with the studies of Ben-David et al [19] and Tarkkila et al [21] whose subjects were able to walk before they could micturate. Our patients were advised not to attempt to pass urine before they had a natural urge to do so.…”
supporting
confidence: 93%
“…The total motor block score (modified Bromage scale; mean Ϯ SD) on the operated and nonoperated sides in patients receiving near isobaric (group 1; n ¼ 30) and hypobaric (group 2; n ¼ 30) bupivacaine (6 mg) for spinal anaesthesia. reported after hyperbaric bupivacaine spinal anaesthesia [5,21]. In our present study, there was no evidence of transient neurological sequelae.…”
supporting
confidence: 50%
“…Although spinal anaesthesia can be achieved with hypo-and hyperbaric solutions of bupivacaine [10,[18][19][20][21], transient neurological symptoms have been Anaesthesia, 1999, 54, pages 540-545 K. S. Kuusniem et al…”
SummaryThe results of studies on the effect of volume, concentration or total dose of local anaesthetic on the spread of spinal anaesthesia are inconclusive. Most support the assumption that the total dosage is more important than the volume. We compared low-dose bupivacaine (6 mg) in 0.5% and 0.18% solutions as sole anaesthetic to achieve predominantly unilateral spinal anaesthesia for knee arthroscopy. Sixty patients were randomly allocated to two groups to receive either 1.2 ml 0.5% bupivacaine (6 mg) (n ¼ 30) or 3.4 ml 0.18% hypobaric bupivacaine (6.1 mg) (n ¼ 30). Drugs were administered at the L 3-4 interspace with the patient in the lateral position. Patients remained in this position for 20 min before being turned supine for the operation. Spinal block was assessed by pinprick and modified Bromage scale and compared between the operated and nonoperated sides. No significant changes were found in the spread or duration of sensory or motor block (p > 0.05). The haemodynamic changes were also similar between the groups. The same pinprick level of analgesia, degree of motor block and duration of spinal anaesthesia was obtained with bupivacaine (6 mg) in low (1.2 ml) or high (3.4 ml) volumes. The ideal spinal anaesthesia for ambulatory surgery should provide good surgical anaesthesia with rapid recovery from sensory and motor block [1]. Lignocaine has been widely advocated for ambulatory anaesthesia but there are concerns about possible neurotoxicity. Recent editorials have questioned the use of hyperbaric 5% lignocaine for spinal anaesthesia [2][3][4]. In contrast, the frequency of radiating backache after bupivacaine has been reported as less than 1% [5,6]. There is increasing interest in the use of small doses of bupivacaine for spinal anaesthesia.There has been controversy concerning the relationship between volume, concentration and total dose of spinally administered drugs. Most of the studies suggest that the total dosage is more important than the volume [7][8][9]. In these studies, the doses of bupivacaine were fairly large. Sheskey et al. used 10, 15 and 20 mg doses [7] and Bengtsson et al. used bupivacaine 22.5 mg [8]. In the study of Cherng et al., plain bupivacaine 15 mg was diluted with cerebrospinal fluid (CSF) [9]. The effect of volume on spinal anaesthesia when a small dose (5-10 mg) of hypobaric bupivacaine is used has not been investigated.In a previous study, we achieved predominantly unilateral spinal anaesthesia with minimal sensory and motor block on the nonoperated side using a low dose of hypobaric 0.18% bupivacaine [10]. We have now compared low-dose bupivacaine (6 mg) in two volumes for predominantly unilateral spinal anaesthesia for day-case knee arthroscopy.
Methods
“…Hyperbaric bupivacaine 0.5% in a dose of 10 mg was chosen for spinal anesthesia because it provides tolerance to pneumatic tourniquet for 70 min (21), which is usually enough for arthroscopic anterior cruciate ligament-reconstruction and other orthopedic lower limb surgery. This dose may, however, delay the ability to void in some patients (22). In our study, the time of the first micturition in both groups was comparable to previous results (22), despite the much smaller amount of infused free water in the HS group.…”
Section: Discussionsupporting
confidence: 78%
“…This dose may, however, delay the ability to void in some patients (22). In our study, the time of the first micturition in both groups was comparable to previous results (22), despite the much smaller amount of infused free water in the HS group. In addition to the ability to maintain adequate MAP, HS solution improves kidney function by reducing renal vascular resistance (23).…”
Hypertonic saline can be used for initial fluid administration before spinal anesthesia. It is effective in smallvolume fluid resuscitation. This randomized doubleblinded study compared the effects of 7.5% hypertonic saline (HS) and 0.9% normal saline (NS) in doses containing 2 mmol/kg of sodium in 40 ASA physical status I-II patients undergoing arthroscopy or other lower limb surgery under spinal anesthesia. We infused 1.6 mL/kg of HS or 13 mL/kg of NS for initial fluid administration before spinal anesthesia induced with a 10-mg dose of 0.5% hyperbaric bupivacaine. Etilefrine was administered to maintain mean arterial pressure at Ն80% of its control value. Systolic and diastolic blood pressure, heart rate, and cardiac index did not differ between the groups, and the amount of etilefrine administered was similar in the treatment groups. In all our patients, the plasma sodium concentrations were within the normal range after surgery and serum osmolality was within the normal range after spinal anesthesia. The time and the volume of the first micturition were similar in both groups, despite the much smaller amount of infused free water in the HS group. We conclude that 7.5% HS was as good as NS for the initial fluid administration before spinal anesthesia when the amount of sodium was kept unchanged.
Under the present study conditions, hyperbaric prilocaine 2% was superior to hyperbaric bupivacaine 0.5% due to a shorter effect profile but otherwise equivalent quality of block. However, puncture in a sitting position and positioning with elevated torso for restriction of the cranial expansion of block spread might cause an enhanced sacral block with delayed recovery of bladder function.
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