Home artificial nutrition in palliative care cancer patients: Impact on survival and performance status

Ruggeri, E; Giannantonio, Marilena; Agostini, F.; Ostan, Rita; Pironi, Loris; Pannuti, Raffaella

doi:10.1016/j.clnu.2020.02.021

Cited by 54 publications

(69 citation statements)

References 45 publications

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“…Similar results were obtained as those in the studies using 500 mg/d apatinib with DCR of 83.3% and a median PFS of 5 months. PS is highly associated with prognosis in the palliative treatment of cancer patients; a deteriorated PS indicates poor survival 20 . Likewise, we observed that case 4 with deteriorated PS had a rapid disease progression, and other patients with SD showed no change in PS.…”

Section: Case Summarysupporting

confidence: 65%

Low‐dose apatinib and tegafur‐gimeracil‐oteracil as palliative treatment in recurrent cervical cancer patients with poor performance status: A case series

Wang

Shang

et al. 2020

J Clin Pharm Ther

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What is known and objective A large proportion of recurrent cervical cancer (RCC) patients present with poor performance status (PS) after comprehensive treatments, which usually prevents them from opting for clinical trials. We retrospectively analysed the effect and safety of low‐dose apatinib and tegafur‐gimeracil‐oteracil (TGO) in the treatment of these patients. Case summary Six patients treated with low‐dose apatinib and TGO showed a disease control rate of 83.3% and grade 1‐2 adverse events (AEs). What is new and conclusion This case series indicates that low‐dose apatinib and TGO could be considered as palliative therapy for RCC patients with poor PS.

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Section: Case Summarysupporting

confidence: 65%

Low‐dose apatinib and tegafur‐gimeracil‐oteracil as palliative treatment in recurrent cervical cancer patients with poor performance status: A case series

Wang

Shang

et al. 2020

J Clin Pharm Ther

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“…That is why, usage of AN may be justified in patients that receive palliative care, are undernourished, and have a reasonable life expectancy, if it would improve their quality of life [19,20]; but there are not enough good quality studies that help to provide recommendations about EN by nasogastric tube in patients that receive palliative care [21]. Occasionally, it is considered an unnecessary treatment that only contributes to extend suffering, and that this treatment should not be used [22].…”

Section: Discussionmentioning

confidence: 99%

Nurse and Nursing Students’ Opinions and Perceptions of Enteral Nutrition by Nasogastric Tube in Palliative Care

Sánchez-Sánchez¹,

Ramírez-Vargas²,

Peinado-Canas³

et al. 2021

Nutrients

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It is widely accepted that nursing staff play a key role in palliative care (PC). The use of Nasogastric tubes (NG tubes) for Enteral Nutrition (EN) administration is still controversial in patients who receive PC. The aim of this study was to describe nurses’ and nursing students´ opinions and perceptions about EN using NG tubes in adult patients in palliative care. To achieve this goal, a cross-sectional descriptive study was carried out. A self-administered, semi-structured questionnaire intended for nurses and nursing students was used. Data was descriptively and inferentially analyzed using a chi-square test to determine the differential frequency of responses. In addition, a multivariate logistic regression model was also conducted. A total of 511 participants completed the questionnaire. Among them, nursing staff represented 74.9% (n = 383) whereas nursing students were 25.1% (n = 128). When life expectancy was above six months, 90.0% (n = 460) reported that EN using NG should be implemented. In contrast, when life expectancy is less than a month, 57.5% (n = 294) discouraged it. Significant differences within groups were found when life expectancy was <1 month (p = 0.044). It was also found that 491 participants (96.1%) reported that patient´s autonomy must be carefully respected for deciding whether continuing EN by NG tube or not. Finally, it was concluded for both nurses and nursing students that life expectancy should be the mean reason for implementing and withdrawing EN by NG tube. Major differences were found regarding when it should be ceased, suggesting perceptions may change as nurses graduate and move into their professional roles.

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“…Se ha demostrado ampliamente que las terapias nutricionales guiadas y controladas por equipos especializados y multidisciplinares alcanzan mejores resultados (9)(10)(11)(12) . En general, y teniendo en cuenta que la fisiopatología y los tratamientos están fuera del alcance de este trabajo, las complicaciones del soporte nutricional se pueden clasificar en:…”

Section: Complicaciones Del Apoyo Nutricionalunclassified

“…Mientras que algunos de ellos muestran una mejora en los dominios de la CdV, otros no informaron de ningún efecto con las intervenciones. Los estudios sobre NP y, más concretamente, en la NP domiciliaria informaron de beneficios en los índices de CdV (6)(7)(8)(9)46) .…”

Section: Cáncer Y Tratamiento Oncológicounclassified

Recomendaciones nutricionales en cuidados paliativos para pacientes con enfermedades avanzadas y al final de la vida

Muscogiuri¹,

Barrera²,

Carignano³

et al. 2021

Rev. Nutr. Clin. Metab.

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Los cuidados paliativos (CP) se basan en un abordaje multidisciplinar del paciente y su familia para prevenir y aliviar el sufrimiento del paciente, al promover y mantener una óptima calidad de vida hasta la muerte. La alimentación desempeña un papel fundamental en la vida de las personas. Más allá de la nutrición, el hecho de que las personas moribundas tengan anorexia como parte de sus síntomas es difícil de aceptar, ya que significa admitir la muerte. Un plan multidisciplinar de nutrición es fundamental, que se adapte al estadio de la enfermedad, siempre considerando que los beneficios deben superar los posibles efectos adversos. Como parte integral de la CP, la nutrición e hidratación artificiales (NHA) pueden aumentar la supervivencia y mejorar la calidad de vida en pacientes seleccionados en función de su patología. Por tanto, el soporte nutricional debe prescribirse de acuerdo con el estadio de la enfermedad del paciente y los requerimientos energéticos y proteicos, analizando la tolerabilidad y, sobre todo, respetando los deseos del paciente, la familia y el cuidador. Es fundamental conocer sus preferencias y lograr una comunicación eficiente dentro del equipo de salud. Al hacerlo, es posible alcanzar un entendimiento compartido de los objetivos del tratamiento paliativo entre todos los miembros involucrados. Esta revisión narrativa tiene como objetivo describir las recomendaciones nutricionales generales y específicas en la etapa avanzada y al final de la vida de algunas de las enfermedades primarias en las que los CP desempeñan un papel vital para ofrecer un tratamiento completo a estos pacientes específicos.

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Home artificial nutrition in palliative care cancer patients: Impact on survival and performance status

Cited by 54 publications

References 45 publications

Low‐dose apatinib and tegafur‐gimeracil‐oteracil as palliative treatment in recurrent cervical cancer patients with poor performance status: A case series

Low‐dose apatinib and tegafur‐gimeracil‐oteracil as palliative treatment in recurrent cervical cancer patients with poor performance status: A case series

Nurse and Nursing Students’ Opinions and Perceptions of Enteral Nutrition by Nasogastric Tube in Palliative Care

Recomendaciones nutricionales en cuidados paliativos para pacientes con enfermedades avanzadas y al final de la vida

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