Abstract. It is an elementary fact that the action by holomorphic automorphisms on C n is infinitely transitive, i.e., m-transitive for any m ∈ N. The same holds on any Stein manifold with the holomorphic density property X. We study a parametrized case: we consider m points on X parametrized by a Stein manifold W , and seek a family of automorphisms of X, parametrized by W , putting them into a standard form which does not depend on the parameter. This general transitivity is shown to enjoy an Oka principle, to the effect that the obstruction to a holomorphic solution is of a purely topological nature. In the presence of a volume form and of a corresponding density property, similar results for volume-preserving automorphisms are obtained.