Holography: an interpretation from the phase-space point of view

Situ, Guohai; Sheridan, John T.

doi:10.1364/ol.32.003492

Cited by 29 publications

(14 citation statements)

References 18 publications

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“…(1) are the 0th order terms, and the last two terms carry the information about the object wavefront. And these two terms can be separated in the Fourier spectrum when the reference beam is adjusted to some suitable angles 23 . Thus one can use a band-pass filter to select the term with , and eventually reconstruct the whole wavefront of the object.…”

Section: Resultsmentioning

confidence: 99%

Fast modal decomposition for optical fibers using digital holography

Lyu

Lin

et al. 2017

Sci Rep

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Eigenmode decomposition of the light field at the output end of optical fibers can provide fundamental insights into the nature of electromagnetic-wave propagation through the fibers. Here we present a fast and complete modal decomposition technique for step-index optical fibers. The proposed technique employs digital holography to measure the light field at the output end of the multimode optical fiber, and utilizes the modal orthonormal property of the basis modes to calculate the modal coefficients of each mode. Optical experiments were carried out to demonstrate the proposed decomposition technique, showing that this approach is fast, accurate and cost-effective.

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Section: Resultsmentioning

confidence: 99%

Fast modal decomposition for optical fibers using digital holography

Lyu

Lin

et al. 2017

Sci Rep

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“…These two techniques independently enabled twin-image free reconstruction of the micro-objects from their raw holograms, as already illustrated in the previous section. These digital reconstruction approaches can actually be considered to be part of a broader umbrella of interferometric and noninterferometric phase-retrieval techniques 17,18. In both of these methods, the transfer function of the Rayleigh–Sommerfeld integral19 without any approximations has been used to back-propagate the fields.…”

Section: Experimental Methodsmentioning

confidence: 99%

High-Throughput Lens-Free Blood Analysis on a Chip

Seo

Isikman²,

Şencan³

et al. 2010

Anal. Chem.

130

100

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We present a detailed investigation of the performance of lens-free holographic microscopy toward high-throughput on-chip blood analysis. Using a spatially incoherent source that is emanating from a large aperture, automated counting of red blood cells with minimal sample preparation steps at densities reaching up to ~0.4 × 10 6 cells/μL is presented. Using the same lens-free holographic microscopy platform, we also characterize the volume of the red blood cells at the single-cell level through recovery of the optical phase information of each cell. We further demonstrate the measurement of the hemoglobin concentration of whole blood samples as well as automated counting of white blood cells, also yielding spatial resolution at the subcellular level sufficient to differentiate granulocytes, monocytes, and lymphocytes from each other. These results uncover the prospects of lens-free holographic on-chip imaging to provide a useful tool for global health problems, especially by facilitating whole blood analysis in resource-poor environments.Together with several recent contributions, lens-free imaging 1-11 is now becoming more and more important, especially for cytometry and microscopy applications. Among others, one field that would enormously benefit from lens-free on-chip digital imagers is the field of microfluidics. 12,13 Over the past decade, microfluidics has revolutionized the available toolset to handle cells by significantly reducing the required device and reagent volumes, as well as the associated costs. Lens-free on-chip imaging could provide further reduction in the size and the cost of these microfluidic systems, while, at the same time, improving the throughput of imaging and/or characterization. To complement these advances in lens-free imaging and microfluidics, recently, we have introduced an on-chip holographic microscopy platform with subcellular resolution over a large field of view (~24 mm 2 ). [8][9][10][11] In this technique, by controlling the spatial coherence of the illumination source (which can be a simple lightemitting diode), we record the two-dimensional (2D) holographic diffraction signature of each cell or microparticle on an opto-electronic sensor array without the use of any lenses or lasers (see Figure 1). This recorded holographic pattern is then rapidly processed using a customdeveloped algorithm 9,10 to perform wide field-of-view (FOV) microscopy of semitransparent objects such as blood cells on the chip.Providing a spatial resolution of ~1.4-1.5 μm, 9,11 which is comparable to a 10× objective-lens with a numerical aperture of ~0.1-0.2 at ~500-600 nm, but with an order-of-magnitude-larger * Author to whom correspondence should be addressed. FOV (e.g., 24 mm 2 vs ~2 mm 2 ), our lens-free microscopy platform is capable of imaging a large number of cells simultaneously. As a result, this system meets the requirements and needs of whole blood analysis applications, which inevitably necessitate high-throughput imaging and characterization. Toward this end, here, we presen...

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“…PSO is an approximate phase space representation firmly grounded in the more physical WDF. While other such representation of signals exist and have been used to interpret optical systems, i.e., the Ambiguity function [2], the WDF and the PSO offer simplicity. Furthermore, with use they can provide intuitive insights and suggest practical applications.…”

Section: Measurement: Phase Motion and Specklementioning

confidence: 99%

A Review of Some Recent Work in the Area of Imaging and Optical Signal Processing

Sheridan

2010

Imaging Systems

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A concise review is presented of research recently carried out within our research group. Topics discussed include: (i) Imaging through turbulent media using Lucky Imaging combined with synthetic apertures; (ii) Numerical algorithms and simulation of quadratic phases systems, i.e. the Fast Linear Canonical Transform, appropriate sampling, aliasing and the Wigner Distribution Function; (iii) Controlling speckle in such optical systems and speckle based metrology; (iv) Digital holographic systems and their application; and (v) Optical encryption and multiplexing.

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Holography: an interpretation from the phase-space point of view

Cited by 29 publications

References 18 publications

Fast modal decomposition for optical fibers using digital holography

Fast modal decomposition for optical fibers using digital holography

High-Throughput Lens-Free Blood Analysis on a Chip

A Review of Some Recent Work in the Area of Imaging and Optical Signal Processing

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