Multi-millennial climate changes were relatively minor over the mid-late Holocene in the British Isles, because orbitally forced insolation changes were smaller than those at higher latitudes. Centennial climate variability is thus likely to have exerted a greater influence on the environment and human society of the region. Proxy climate records from the British Isles covering the last 4500 years are assembled and re-evaluated with the aim of identifying centennial climate variability reflected by multi-proxy indicators. The proxies include bog oak populations, peatland surface wetness, flooding episodes from fluvial deposits, speleothem band width and oxygen isotopes, chironomids from lake sediments and sand and dune deposition. Most proxies reflect water balance rather than temperature alone, and records predominantly reflect warm season climate. A series of twelve key periods of enhanced precipitation-evaporation (P-E) are identified by their presence in two or more proxy records.Variability in P-E is much greater than that shown by temperature proxies and there is no necessary association between warm/cool and dry/wet periods. Although the data for temperature are less robust than those for P-E, a series of key temperature changes are