Holmium Laser Enucleation of the Prostate: Results at 6 Years

Gilling, Peter; Aho, Tev; Frampton, Christopher; King, Colleen J.; Fraundorfer, Mark R.

doi:10.1016/j.eururo.2007.04.052

Cited by 204 publications

(117 citation statements)

References 29 publications

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“…The results of HoLEP, as evidenced by PSA data, TRUS, the weight of tissue resected, urodynamic variables and data from many randomized trials, systematic reviews and meta-analyses, confirmed the effectiveness and durability of this technique [2][3][4][5][6][7]. HoLEP reproduces the removal of the whole obstructing adenoma (transitional zone) of the prostate by surgical enucleation, similar to the technique of using the index finger in open prostatectomy.…”

Section: Introductionmentioning

confidence: 76%

Holmium Laser Enucleation of the Prostate: Modified Technical Aspects

2010

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Section: Introductionmentioning

confidence: 76%

Holmium Laser Enucleation of the Prostate: Modified Technical Aspects

2010

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“…6-month outcome data using HoLEP for IPSS, Qmax and PVR are typically À70, þ 184 and À74%, respectively. 9 Both the KTP and Ho:YAG lasers are associated with durable long-term results. 4,9 Significant improvement in the patients' QoL was reported postoperatively.…”

Section: Discussionmentioning

confidence: 99%

“…9 Both the KTP and Ho:YAG lasers are associated with durable long-term results. 4,9 Significant improvement in the patients' QoL was reported postoperatively. Similar results have been reported with other lasers.…”

Section: Discussionmentioning

confidence: 99%

Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

Leonardi¹

2009

Prostate Cancer Prostatic Dis

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This study examined efficacy and safety of the 980 nm side-firing diode laser operating at a power of 100 W in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). Patients were selected for surgery on the basis of maximum urinary flow rate (Qmax) p15 ml/s or transvesically measured post-voiding residual volume (PVR) 4100 ml in conjunction with an International Prostate Symptom Score (IPSS) 47. Laser therapy was conducted under spinal anaesthesia. Qmax, IPSS, prostate volume, PVR, IPSS-Quality of Life (QoL) questionnaire and ejaculatory function were measured at baseline and at 1, 3, 6 and 12 months post-laser therapy. A total of 52 consecutive patients aged 52-65 years with mean (s.d.) prostate volume of 45.14 (9.15) g were treated. All patients were able to leave the hospital at a mean (s.d.) of 5 (2) h after the procedure. Mean (s.d.) follow-up was 100 (75.49) days. A significant reduction in IPPS was reported at 1 month (Po0.0001) and this was maintained through to 6 months. Significant durable improvements in Qmax, PVR and IPSS-QoL score were also reported for all patients (Po0.0001). No severe complications were reported, including any cases of urinary incontinence or significant irritative symptoms. None of the patients complained of a worsening of erectile function. This early experience in a pilot study with the 980 nm diode laser seems promising in the short-term and long-term outcome is being monitored.

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“…[14][15][16] Other reports have documented that HoLEP is as durable as open prostatectomy at more than 5-year follow-up. 8,14,17 Furthermore, HoLEP has shown that efficacy and safety are independent of prostate size under about 100 or more performances. [2][3][4][5] Kuntz 18 described that HoLEP has doubtless consigned TURP and open prostatectomy operations to the past for all urologists who manage to complete the learning curve; however, HoLEP has been perceived to be difficult to learn, 6,7 and its difficulty seems to depend on prostate size.…”

Section: Discussionmentioning

confidence: 99%

The relationship between the reproducibility of holmium laser enucleation of the prostate and prostate size over the learning curve

Haraguchi

Takenaka

Yamazaki

et al. 2009

Prostate Cancer Prostatic Dis

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The purpose of this study was to analyze the relationship between the reproducibility of holmium laser enucleation of the prostate (HoLEP) and prostate size over the learning curve. We compared the outcome among three institutions in three subgroups on the basis of the weight of tissue retrieved. There were no significant differences in operating time, efficiency of the procedure, decrease in hemoglobin level and postoperative urinary incontinence among three institutions, only in patients with prostates X20 g-o40 g retrieved. Our data indicate that HoLEP is more reproducible in patients with a moderate-sized prostate over the learning curve.

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Holmium Laser Enucleation of the Prostate: Results at 6 Years

Cited by 204 publications

References 29 publications

Holmium Laser Enucleation of the Prostate: Modified Technical Aspects

Holmium Laser Enucleation of the Prostate: Modified Technical Aspects

Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

The relationship between the reproducibility of holmium laser enucleation of the prostate and prostate size over the learning curve

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