Hollow mesoporous silicas as a drug solution delivery system for insoluble drugs

Synthesis of Magnetic Fe3O4@hierarchical Hollow Silica Nanospheres for Efficient Removal of Methylene Blue from Aqueous Solutions

“…Recently, hollow spheres have received significant attention due to their potential applications in wide areas such as drug delivery, 13,14 photonics, 15 gas sensor, 16 catalysis, 17−19 and adsorbance. 20 Among these hollow sphere materials, the hollow silica spheres are of especial interest in drug delivery and adsorbance due to their greater drug loading volumes and better adsorption abilities compared with conventional silica materials.…”

Sol–gel microencapsulation of oil phase with Pickering and nonionic surfactant based emulsions

“…Regardless the impregnation process, capsules need to have sufficient mechanical properties to resist to stress during utilization. Silica shells or matrices are frequently used to encapsulate various types of active agents such as dyes [7], drugs [8], enzymes [9], bacteria [10] or fire retardant [3], and are widely used in cosmetics formulation because of their biocompatibility and limited toxicity [11]. Moreover, they exhibit high mechanical properties [12], excellent chemical and thermal stabilities with limited release of toxic gases during decomposition.…”

Liquisolid systems and aspects influencing their research and development

“…Chen et al (31) successfully used an ordered mesoporous carrier as coating material to formulate liquisolid systems containing carbamazepine as a model drug, PEG 400 as a non-volatile solvent and MCC or starch 1500 as carrier materials. The significant improvement of drug loading and dissolution rate demonstrated that those formulations could provide enhanced dissolution of poorly water-soluble drugs (31,74).…”