2017
DOI: 10.3889/oamjms.2017.136
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Hoigne Syndrome Caused by Intralesional Meglumine Antimoniate

Abstract: Hoigne syndrome (HS) is the term coined to describe an acute, non-allergic, psychiatrically based reaction occurring with a wide list of medications, mainly antibiotics. Since its first description by Hoigne and Schoch in 1959, few cases have been reported in medical literature and, although antimicrobials are commonly used, very rarely in dermatology. The authors describe the first case occurred after intralesional administration of meglumine antimoniate and briefly discuss the pathogenetic hypotheses on this… Show more

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Cited by 5 publications
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“…Among penicillins, piperacillin and tazobactam appear to be most associated with neurotoxic events, with several reported cases. Hoigne's syndrome is an acute psychotic, toxic, nonallergic reaction most commonly associated with procaine penicillin [ 6 ]. Patients with advanced renal failure are particularly at increased risk.…”
Section: Discussionmentioning
confidence: 99%
“…Among penicillins, piperacillin and tazobactam appear to be most associated with neurotoxic events, with several reported cases. Hoigne's syndrome is an acute psychotic, toxic, nonallergic reaction most commonly associated with procaine penicillin [ 6 ]. Patients with advanced renal failure are particularly at increased risk.…”
Section: Discussionmentioning
confidence: 99%