2008
DOI: 10.1007/s00063-008-1003-5
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Hohes Fieber, Panzytopenie und Splenomegalie 8 Monate nach einem Mallorca-Urlaub

Abstract: Visceral leishmaniasis is an important differential diagnosis for the clinical triad of fever, pancytopenia, and splenomegaly. An accurate travel history is therefore of paramount importance. Without treatment, the case fatality rate is high. A complete recovery is usually achieved with adequate therapy (liposomal amphotericin B, miltefosine).

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Cited by 7 publications
(6 citation statements)
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“…[ 22 ] Travelers to endemic areas are at risk. [ 23 24 25 26 27 28 29 30 ] Ocular findings in cutaneous leishmaniasis indicate a local phenomenon due to the initial site of the bite near the eyelids. Ptosis, cicatricial ectropion or entropion, bilateral lagophthalmia, and chronic ulcerative blepharoconjunctivitis have been described.…”
Section: Resultsmentioning
confidence: 99%
“…[ 22 ] Travelers to endemic areas are at risk. [ 23 24 25 26 27 28 29 30 ] Ocular findings in cutaneous leishmaniasis indicate a local phenomenon due to the initial site of the bite near the eyelids. Ptosis, cicatricial ectropion or entropion, bilateral lagophthalmia, and chronic ulcerative blepharoconjunctivitis have been described.…”
Section: Resultsmentioning
confidence: 99%
“…Gegenwär-tig gilt liposomales Amphotericin B als Mittel der ersten Wahl (unabhängig vom HIV-Serostatus) [7,10,16]. Es existieren verschiedene Therapieschemata [2,3,8,11], möglicherweise ist im Einzelfall auch eine hochdosierte Einmalgabe von liposomalem Amphotericin B effizient [16]. Unter der Therapie sind engmaschige Laborkontrollen der Elektrolyte und der Nierenretentionsparameter obligat.…”
Section: Leishmania-donovani-komplexunclassified
“…Miltefosin ist ein Phospholipid, das ursprünglich als Tumortherapeutikum entwickelt wurde und wahrscheinlich hemmend auf die Mem-branSynthese der Leishmanien wirkt [7,12]. Pancytopenia, hepatosplenomegaly and dry cough after breast cancer 5 History and clinical findings: A 71-year-old woman had suffered for 6 weeks from fatigue, dry cough and fever.…”
Section: Therapie Und Prognoseunclassified
“…Neben langsam progredienten Verläufen, kann es auch zu fulminant septischen Verläufen kommen [5]. [9,12].…”
Section: Introductionunclassified
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