Hodgkin's lymphoma presents as an inguinal abscess: a case report and literature review

Abstract

Lymphadenitis with suppuration is a rare presentation of Hodgkin's lymphoma with few cases reported in the literature. We report two cases of Hodgkin's lymphoma in two male members of the same family. They presented initially with clinical features suggesting infective inguinal lymphadenitis and then the picture was indistinguishable from inguinal abscess. The diagnosis was made after drainage of the pus and excision of the involved lymph node. The histopathology of the excised lymph node showed Hodgkin's lymphoma-nodular sclerosis for both brothers. After careful staging of both patients, the disease found to be localised to the inguinal group of lymph nodes. The patients referred to the haematologist for chemotherapy and they recovered after treatment.

Lymph Node Abscessation Secondary to Neoplasia in Two Dogs

“…In evaluating human patients, a deep neck abscess should be considered a differential diagnosis if severe, acute pain is reported, upper respiratory tract infection, trauma associated with the head or mouth, respiratory distress, dysphagia, asymmetry of the neck, lymphadenopathy, cranial nerve involvement, pyrexia, tachypnoea, or immunosuppression [ 7 ]. In human medicine, lymph node abscesses have been associated with nasopharyngeal carcinoma, Hodgkin's lymphoma, B-cell lymphoma, squamous cell carcinoma, and carcinoma of unknown primary [ 8 , 11 – 13 ]. Both dogs presented to the teaching hospital for lethargy, hyporexia to anorexia, and stridor while at rest.…”

Hodgkin’s lymphoma with multifocal Staphylococcus aureus infection in a 29-year-old male — a case study

“…After surgical treatment and targeted antibiotic therapy, they retreated and appeared in a different location. There are available in medical literature the case reports of HL symptoms, especially the nodular sclerosis form with abscesses of various locations: abscess in the chest wall, liver, lung, spleen, axillary region, or pancreas [10][11][12][13][14][15]. The cultures of such abscesses were mostly aseptic, which indicated their non-infectious aetiology and should suggest the widening of the diagnosis.…”