Hodgkin's disease of the breast

Reed‐sternberg cells in breast FNA of a patient with left breast mass

“…13 B symptoms were reported in only six reports. 3,5,10,13,15 However, presence of B symptoms (weight loss, intermittent fever and profuse night sweating) correlated with worse prognosis in Hodgkin's lymphoma of breast as five of these patients exhibiting B symptoms died on average of 8 months after initial presentation and diagnosis. 3,5,10,15 Laboratory findings related to worse prognosis such as elevated ESR, low serum albumin, low hemoglobin, and low lymphocyte count were reported in few cases.…”

“…24 There are 30 cases reported in the literature up to date. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Demographic analysis of the cases reported in literature up to date showed that the mean age of patients with Hodgkin's lymphoma in breast was 33.5 (SD 16.6) years. Two male patients were reported.…”

“…A total of 30 cases are reported in Western literature. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Due to this scarcity, each case report published since Kuckens in 1928 relies on a variety of staging system, treatment options, and morphological criteria for diagnosis of Hodgkin's lymphoma. We report a case of extranodal Hodgkin's lymphoma of the breast without palpable lymphadenopathy.…”

What’s new on primary Hodgkin’s lymphoma of the breast? A case report and review of the literature

“…The first case in literature of primary HL of the breast was described by Kueckens [11] in 1928, then in a time lapse of 32 years (from 1928 to 1960) only other six cases were reported [12] , [13] , [14] , [15] , [16] , [17] .…”