Hodgkin's Disease in a Married Couple

Hodgkin’s Disease and Mycosis Fungoides in a Married Couple

“…There have been numerous reports in which blood relatives [4,9] and several instances where husband and wife [2,8] or patients related only by marriage [7] have developed Hodgkin's disease. Also, there are many reports of clus tering of cases of Hodgkin's disease in other than family members [5,14].…”

“…Epidemiological studies have recently demonstrated clustering of cases of Hodgkin's disease [2,4,5,[7][8][9]14]. There are also rare reports of clustering of cases of mycosis fungoides [1,3,11].…”

The occurrence of multiple lymphoreticular and hematological malignancies in the same households

“…Our series of 12 probable spouse pairs increases the total number of such spouse pairs in the medical literature to about 40 (Street & Allen, 1950;Mazur & Strauss, 1951;Devore & Doan, 1957;Milham, 1964;Amos et al, 1967;Kyle et al, 1971;Berliner & Dristenfeld, 1972;Dworsky & Henderson, 1974;Pietruszk et al, 1976;Hazen & Michel, 1977;Ly et al, 1978;Kardinal, 1978;Wray et al, 1979;Brugiatelli et al, 1980;Kefford et al, 1980;Dougan et al, 1980). Previously, the largest reported series of such malignancies occurring in spouse pairs was 7, as reported by Milham (1964).…”